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猫与草酸钙:上下尿路结石病的管理策略

Cats and calcium oxalate: strategies for managing lower and upper tract stone disease.

作者信息

Palm Carrie, Westropp Jodi

机构信息

UC Davis School of Veterinary Medicine, Department of Veterinary Medicine and Epidemiology, Davis, CA 95616, USA.

出版信息

J Feline Med Surg. 2011 Sep;13(9):651-60. doi: 10.1016/j.jfms.2011.07.018.

Abstract

PRACTICAL RELEVANCE

Calcium oxalate (CaOx) containing stones are among the most common of the urinary tract stones identified in cats.

RISK FACTORS

Risk factors for CaOx stone formation include such things as breed, gender and diet; stress and obesity have also been hypothesized to be risk factors for this disease.

MANAGEMENT APPROACH

A tailored, individual management strategy for preventing CaOx stone recurrence is important and should include addressing the diet, environment and any other comorbid conditions present. Increasing the cat's moisture intake is one of the key mechanisms for preventing recurrence.

CLINICAL CHALLENGES

CaOx ureterolithiasis has emerged as a difficult and sometimes life-threatening problem for cats. In those cats where stones are found incidentally, periodic monitoring may be required to assess for disease progression. Interventional procedures such as ureteral stent placements are now increasingly being performed for recurrent cases or those with larger stone burdens. Periodic radiographs for more severe cases and frequent client communication can help ensure successful outcomes for cats with lower and upper CaOx stone disease.

EVIDENCE BASE

Limited evidence-based studies are published regarding management of feline upper and lower urinary tract CaOx stone disease, making this a difficult condition to manage in some cats. Studies designed to evaluate the relationship to dietary modifications, medical management, stress, obesity and surgical techniques are warranted in cats with upper and lower urinary tract CaOx stones.

摘要

实际相关性

草酸钙(CaOx)结石是猫中最常见的泌尿道结石之一。

风险因素

CaOx结石形成的风险因素包括品种、性别和饮食等;压力和肥胖也被认为是该疾病的风险因素。

管理方法

制定个性化的预防CaOx结石复发的管理策略很重要,应包括调整饮食、环境以及处理任何其他并存疾病。增加猫的水分摄入量是预防复发的关键机制之一。

临床挑战

CaOx输尿管结石已成为猫的一个棘手且有时危及生命的问题。对于那些偶然发现结石的猫,可能需要定期监测以评估疾病进展。对于复发病例或结石负荷较大的病例,现在越来越多地进行输尿管支架置入等介入手术。对于更严重的病例进行定期X光检查并与主人频繁沟通,有助于确保患有上、下CaOx结石疾病的猫获得成功治疗结果。

循证依据

关于猫上、下泌尿道CaOx结石疾病管理的循证研究有限,这使得在一些猫中管理这种疾病变得困难。有必要开展旨在评估饮食调整、药物治疗、压力、肥胖与手术技术之间关系的研究,用于患有上、下泌尿道CaOx结石的猫。

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