应用软凝块、聚乙二醇酸毡和纤维蛋白胶预防远端胰腺切除术后胰瘘。
Soft coagulation, polyglycolic acid felt, and fibrin glue for prevention of pancreatic fistula after distal pancreatectomy.
机构信息
Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
出版信息
Surg Today. 2011 Sep;41(9):1224-7. doi: 10.1007/s00595-010-4433-7. Epub 2011 Aug 26.
PURPOSE
To evaluate the effectiveness of using soft coagulation followed by the application of polyglycolic acid (PGA) felt and fibrin glue to prevent pancreatic fistula (PF) after distal pancreatectomy (DP).
METHODS
A soft coagulation system was applied on the cut surface of the pancreas after ligating the main pancreatic duct, followed by the application of layers of PGA felt and fibrin glue on the layers, to prevent the development of a PF after DP.
RESULTS
This technique was applied in nine patients, with mean drain amylase levels of 372 ± 296, 185 ± 209, 54 ± 40, and 47 ± 34 IU/l on days 1, 3, 5, and 7, respectively, after DP. Only one patient (11.1%) showed a Grade A PF on day 3 after surgery; none of the other patients developed a fistula.
CONCLUSIONS
This technique is an effective prophylactic measure to prevent the development of a PF after DP.
目的
评估在结扎主胰管后使用软凝固联合聚乙二醇酸（PGA）毡和纤维蛋白胶预防胰十二指肠切除术后胰瘘（PF）的效果。
方法
在结扎主胰管后，在胰腺切面上应用软凝固系统，然后在各层上应用 PGA 毡和纤维蛋白胶，以预防 DP 后 PF 的发生。
结果
该技术应用于 9 例患者，术后第 1、3、5 和 7 天的引流淀粉酶水平分别为 372±296、185±209、54±40 和 47±34IU/l。仅 1 例（11.1%）患者术后第 3 天出现 A 级 PF，其余患者均未发生瘘。
结论
该技术是预防 DP 后 PF 发生的有效预防措施。
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