Rabeya Y, Abdul-Kahar A H, Leong C F
Department of Diagnostic Laboratory Services, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur.
Malays J Pathol. 2011 Jun;33(1):25-9.
Transfusion is an irreversible event which carries potential benefits as well as risk to the recipient. The objective of this study was to analyse all reported transfusion reactions of the year 2008 in the Blood Bank Unit of Universiti Kebangsaan Malaysia Medical Centre (UKMMC). This is a retrospective study that was carried out by retrieving data from the laboratory information system. A total of 27842 transfusions were documented and the total reported transfusion reactions were 149. The incidence of transfusion reaction was 1 in 187 of all transfusions (0.54%); in which 69 (0.25%) were allergic in nature and 61 (0.22%) were febrile non-haemolytic transfusion reactions (FNHTR). Hypotensive reactions were identified in 6 (0.02%) patients. There were 9 (0.03%) cases reported with haemoglobinuria where no serological evidence of haemolytic transfusion reaction (HTR) was found. One HTR (0.003%) was identified and this was due to an error in patient identification in the ward. Other specified reactions like transfusion-related acute lung injury (TRALI), bacterial infections, Graft verses host disease (GVHD) were not reported. The highest frequency of the reactions occurred in the red cell transfusions which accounted for 111 cases. In conclusion, the incidences of transfusion reactions are low when compared to those reported by other centres.
输血是一个不可逆转的过程，对受血者来说既可能带来潜在益处，也存在风险。本研究的目的是分析马来西亚国民大学医学中心（UKMMC）血库2008年报告的所有输血反应。这是一项回顾性研究，通过从实验室信息系统检索数据来开展。共记录了27842次输血，报告的输血反应总数为149例。输血反应发生率为每187次输血中有1例（0.54%）；其中69例（0.25%）为过敏性质，61例（0.22%）为发热性非溶血性输血反应（FNHTR）。6例（0.02%）患者出现低血压反应。有9例（0.03%）报告出现血红蛋白尿，但未发现溶血性输血反应（HTR）的血清学证据。确诊1例HTR（0.003%），这是由于病房患者识别错误所致。未报告其他特定反应，如输血相关急性肺损伤（TRALI）、细菌感染、移植物抗宿主病（GVHD）。反应发生率最高的是红细胞输血，占111例。总之，与其他中心报告的情况相比，本中心输血反应发生率较低。
