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马来西亚疑似病例中布鲁氏菌病的血清阳性率

Seroprevalance of brucellosis among suspected cases in Malaysia.

作者信息

Jama'ayah M Z, Heu J Y, Norazah A

机构信息

Bacteriology Unit, Institute for Medical Research, Kuala Lumpur, Malaysia.

出版信息

Malays J Pathol. 2011 Jun;33(1):31-4.

PMID:21874749
Abstract

Brucellosis is a zoonotic disease which can be transmitted by direct or indirect contact with infected animal or their products. It is an important public health problem but little is known on brucellosis in the Malaysian population. The aim of this study was to determine the presence of Brucella antibodies using commercial Brucella IgG and IgM ELISA kits (Vircell, SL, Barcelona Spain). A total of 184 sera from suspected patients were received from 16 hospitals in Malaysia over the years 2004 to 2009. Only 10 serum samples (5.4%) were positive for Brucella antibodies in which 5 showed the presence of both IgM and IgG. Most of the positive patients were occupationally involved with animals. This study suggests the seroprevalance of brucellosis among individuals who have contact with infected animals in Malaysia is low.

摘要

布鲁氏菌病是一种人畜共患病,可通过直接或间接接触受感染动物或其产品传播。它是一个重要的公共卫生问题,但马来西亚人群中对布鲁氏菌病的了解甚少。本研究的目的是使用商业化的布鲁氏菌IgG和IgM ELISA试剂盒(西班牙巴塞罗那Vircell公司)检测布鲁氏菌抗体的存在情况。2004年至2009年期间,从马来西亚16家医院共收到184份疑似患者的血清。只有10份血清样本(5.4%)布鲁氏菌抗体呈阳性,其中5份同时存在IgM和IgG。大多数阳性患者的职业与动物有关。本研究表明,在马来西亚与受感染动物有接触的个体中,布鲁氏菌病的血清流行率较低。

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