Gil-Extremera Blas, Cía-Gómez Pedro
Service of Internal Medicine, Hypertension and Lipid Unit, "San Cecilio" University Hospital, Granada, Spain.
Int J Hypertens. 2012;2012:859176. doi: 10.1155/2012/859176. Epub 2011 Aug 16.
Background. The incidence of hypertension in the Western countries is continuously increasing in the elderly population and remains the leading cause of cardiovascular and morbidity. Methods. we analysed some significant clinical trials in order to present the relevant findings on those hypertensive population. Results. Several studies (SYST-EUR, HYVET, CONVINCE, VALUE, etc.) have demonstrated the benefits of treatment (nitrendipine, hydrochrotiazyde, perindopril, indapamide, verapamil, or valsartan) in aged hypertensive patients not only concerning blood pressure values but also the other important risk factors. Conclusion. Hypertension is the most prevalent cardiovascular disorder in the Western countries, and the relevance of receiving pharmacological treatment of hypertension in aged patients is crucial; in addition, the results suggest that combination therapy-nitrendipine plus enalapril-could have more benefits than those observed with the use of nitrendipine alone.
背景。西方国家老年人群中高血压的发病率持续上升，仍是心血管疾病及发病的主要原因。方法。我们分析了一些重要的临床试验，以便呈现高血压人群的相关研究结果。结果。多项研究（SYST-EUR、HYVET、CONVINCE、VALUE等）已证明，治疗（尼群地平、氢氯噻嗪、培哚普利、吲达帕胺、维拉帕米或缬沙坦）对老年高血压患者有益，不仅涉及血压值，还包括其他重要危险因素。结论。高血压是西方国家最常见的心血管疾病，老年患者接受高血压药物治疗至关重要；此外，结果表明联合治疗——尼群地平加依那普利——可能比单独使用尼群地平有更多益处。
