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富营养化和肥胖个体中肺活量测定与六分钟步行试验的相关性。

Correlation of spirometry with the six-minute walk test in eutrophic and obese individuals.

作者信息

Gontijo Patrícia Lúcia, Lima Tiago Pessoa, Costa Thais Ribeiro, Reis Ederson Paulo dos, Cardoso Flavia Perassa de Faria, Cavalcanti Neto Florêncio Figueiredo

机构信息

Universidade Católica de Brasília (UCB), Brasília, DF, Brazil.

出版信息

Rev Assoc Med Bras (1992). 2011 Jul-Aug;57(4):380-6.

PMID:21876918
Abstract

OBJECTIVE

To assess the distance covered by both eutrophic individuals and individuals with different grades of obesity and correlate the data obtained with spirometric values. This study is justified by the existing difficulty in assessing the functional capacity in obese individuals, and by the low cost and good specificity of six-minute walk test (6MWT) in predicting reduced capacity for activities of daily living for any individual.

METHODS

One hundred fifty-four individuals of both genders were assessed after being divided into two groups: G1, obese individuals (n = 93, BMI ≥ 30 kg/m²) and G2, eutrophic individuals (n = 61, BMI 18.5 to 24.99 kg/m²). The 6MWT was performed using the methodology described by the American Thoracic Society (ATS-2002). Spirometry was performed both before and after the application of a bronchodilator agent (BDA) in accordance with the Guidelines for Pulmonary Function Tests by the Brazilian Society of Pneumology and Phthisiology (SBPT-2002). The statistical analysis, consisting of mean, standard deviation, Pearson's correlation, Student's t test and Spearman's correlation, considered p < 0.05.

RESULTS

The 6MWT analysis with spirometry for G1 was positively correlated only with pre- and post-BDA peak expiratory flow rate (PEFR).

CONCLUSION

The present study showed a positive correlation between pre- and post-BDA PEFR and the distance covered in the 6MWT in obese subjects, that is, the higher the PEFR, the higher the physico-functional capacity of the individual, and consequently, the greater the distance covered.

摘要

目的

评估营养正常个体以及不同肥胖等级个体的步行距离,并将所得数据与肺功能测定值进行关联。本研究的合理性在于评估肥胖个体功能能力存在困难,以及六分钟步行试验(6MWT)在预测任何个体日常生活活动能力下降方面成本低且特异性好。

方法

154名男女个体被分为两组后接受评估:G1组为肥胖个体(n = 93,BMI≥30 kg/m²),G2组为营养正常个体(n = 61,BMI 18.5至24.99 kg/m²)。6MWT采用美国胸科学会(ATS - 2002)描述的方法进行。根据巴西肺科和结核病学会(SBPT - 2002)的肺功能测试指南,在使用支气管扩张剂(BDA)前后进行肺功能测定。统计分析包括均值、标准差、Pearson相关性、Student's t检验和Spearman相关性,以p < 0.05为标准。

结果

G1组的6MWT分析与肺功能测定结果仅在使用BDA前后的呼气峰值流速(PEFR)方面呈正相关。

结论

本研究表明,肥胖受试者使用BDA前后的PEFR与6MWT中的步行距离呈正相关,即PEFR越高,个体的身体功能能力越高,因此步行距离越长。

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