Department of Cognitive and Neural Systems, Boston University, Boston, MA 02215, USA.
J Acoust Soc Am. 2011 Aug;130(2):866-82. doi: 10.1121/1.3605549.
This study tests how peripheral auditory processing and spectral dominance impact lateralization of precedence effect (PE) stimuli consisting of a pair of leading and lagging clicks. Predictions from a model whose parameters were set from established physiological results were tested with specific behavioral experiments. To generate predictions, an auditory nerve model drove a binaural, cross correlation computation whose outputs were summed across frequency using weightings derived from past physiological studies. The model predicted that lateralization (1) depends on stimulus center frequency and the inter-stimulus delay (ISD) between leading and lagging clicks for narrowband clicks and (2) changes differently with lead click level for different ISDs. Behaviorally, subjects lateralized narrowband and wideband click pairs whose stimulus parameters were chosen based on modeling results to test how peripheral processing and frequency dominance contribute to lateralization of PE stimuli. Behavioral results (including unique measures with the lead attenuated relative to the lag) suggest that peripheral interactions between leading and lagging clicks on the basilar membrane and strong weighting of cues around 750 Hz influence lateralization of paired clicks with short ISDs. When combined with auditory nerve adaptation, which emphasizes onset information, lateralization of PE click pairs with a short ISD can be well predicted.
本研究测试了外围听觉处理和频谱优势如何影响由一对领先和滞后点击组成的优先效应 (PE) 刺激的侧化。从一个模型的参数进行预测，该模型的参数是根据已建立的生理结果设置的，并用特定的行为实验进行了测试。为了生成预测，听觉神经模型驱动了一个双耳交叉相关计算，其输出使用来自过去生理研究的权重在频率上求和。该模型预测，（1）侧化取决于刺激中心频率和领先与滞后点击之间的刺激间延迟 (ISD) 对于窄带点击，（2）对于不同的 ISD，侧化随领先点击水平的变化而不同。在行为上，研究人员对窄带和宽带点击对进行了侧化，这些点击对的刺激参数是根据建模结果选择的，以测试外围处理和频率优势如何影响 PE 刺激的侧化。行为结果（包括与滞后相比，领先衰减的独特测量）表明，基底膜上领先和滞后点击之间的外围相互作用以及围绕 750 Hz 的强烈线索加权影响了短 ISD 对点击的侧化。当与强调起始信息的听觉神经适应相结合时，短 ISD 的 PE 点击对的侧化可以很好地预测。
