Serviço de Doenças Infecciosas, Hospitais da Universidade de Coimbra, EPE, Avenida Bissaya Barreto e Praceta Prof. Mota Pinto, 3000-075, Coimbra, Portugal.
J Infect Chemother. 2012 Feb;18(1):105-8. doi: 10.1007/s10156-011-0295-1. Epub 2011 Aug 31.
Mediterranean spotted fever (MSF) is a disease caused by Rickettsia conorii and transmitted by the brown dog tick Rhipicephalus sanguineus. It is widely distributed through southern Europe, Africa, and the Middle East. It is an emerging or a reemerging disease in some regions. Countries of the Mediterranean basin, such as Portugal, have noticed an increased incidence of MSF over the past 10 years. It was believed that MSF was a benign disease associated with a mortality rate of 1-3% before the antimicrobial drug era. It was called benign summer typhus. Severe forms were described in 1981, and the mortality rate reached 32% in Portugal in 1997. However, neurological manifestations associated with brain lesions are a rare event. We describe the case of a man with fever, maculopapular rash, a black spot, and hemisensory loss including the face on the left side of the body with brain lesions in the imaging studies.
地中海热（MSF）是由康氏立克次体引起的疾病，通过褐犬蜱（Rhipicephalus sanguineus）传播。它广泛分布于南欧、非洲和中东地区。在一些地区，它是一种新出现或重新出现的疾病。地中海盆地的国家，如葡萄牙，注意到过去 10 年来 MSF 的发病率有所增加。在抗菌药物时代之前，人们认为 MSF 是一种良性疾病，死亡率为 1-3%。它被称为良性夏季斑疹伤寒。1981 年描述了严重的形式，1997 年葡萄牙的死亡率达到 32%。然而，与脑损伤相关的神经系统表现是一种罕见事件。我们描述了一例发热、斑丘疹、黑斑、左侧面部和身体半感觉丧失的男性病例，影像学研究显示脑部病变。
