Huber Lara
Universitätsmedizin der Johannes Gutenberg-Universität Mainz, Institut für Geschichte, Theorie und Ethik der Medizin, Mainz.
Ber Wiss. 2011 Jun;34(2):174-90. doi: 10.1002/bewi.201101502.
In the neurosciences digital databases more and more are becoming important tools of data rendering and distributing. This development is due to the growing impact of imaging based trial design in cognitive neuroscience, including morphological as much as functional imaging technologies. As the case of the 'Laboratory of Neuro Imaging' (LONI) is showing, databases are attributed a specific epistemological power: Since the 1990s databasing is seen to foster the integration of neuroscientific data, although local regimes of data production, -manipulation and--interpretation are also challenging this development. Databasing in the neurosciences goes along with the introduction of new structures of integrating local data, hence establishing digital spaces of knowledge (epistemic spaces): At this stage, inherent norms of digital databases are affecting regimes of imaging-based trial design, for example clinical research into Alzheimer's disease.
在神经科学领域，数字数据库正日益成为数据呈现和传播的重要工具。这一发展归因于基于成像的试验设计在认知神经科学中日益增长的影响，包括形态学和功能成像技术。正如“神经成像实验室”（LONI）的情况所示，数据库被赋予了一种特定的认识论力量：自20世纪90年代以来，数据库被视为促进神经科学数据的整合，尽管本地的数据生产、操作和解释机制也在挑战这一发展。神经科学中的数据库建设伴随着整合本地数据的新结构的引入，从而建立了知识的数字空间（认知空间）：在这个阶段，数字数据库的内在规范正在影响基于成像的试验设计机制，例如对阿尔茨海默病的临床研究。
