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[丹麦制药行业的早期成就——3. 阿尔弗雷德·本松]

[Early achievements of the Danish pharmaceutical industry--3. Alfred Benzon].

作者信息

Grevsen Jørgen V, Kirkegaard Hanne, Kruse Edith, Kruse Poul R

出版信息

Theriaca. 2011(39):7-51.

PMID:21879529
Abstract

The article series provides a written and pictorial account of the Danish pharmaceutical industry's products from their introduction until about 1950. Part 3 deals with products from the company founded by Alfred Benzon in 1849. Alfred Nicolai Benzon owned the Swan Pharmacy in Copenhagen. In 1863 he started an independent company manufacturing branded pharmaceuticals, thus combining the pharmacy's activities with the wholesale business. The family owned the company until 1952, when it was converted into a foundation. After several restructuring rounds, the medicine production business continued as Benzon Pharma A/S until 1990, when Nycomed Pharma A/S bought up all the branded pharmaceuticals. As the first pharmaceutical company in Denmark, Alfred Benzon was an industrial frontrunner in the country at the time, supplying not only the domestic market but foreign markets as well. Alfred Benzon was the first Danish company to produce ether for anesthesia, and malt extract, a dietetic preparation. The high quality of both products made them valuable export articles. In the early 1890s, Alfred Benzon became the first Danish company to start the research-based production of extract of thyroid glands from slaughtered cattle. This was the beginning of a long-standing specialization in producing organotherapeutic substances from animal organs originating from Danish animal husbandry. In 1932 the company had 26 preparations of this type in its range, many of them on the market for several years. These medicine substances included iron preparations and effervescent salts followed by sulfonamides, synthetic hormones and a substance to counteract motion sickness.

摘要

该系列文章以文字和图片的形式介绍了丹麦制药行业从产品问世到1950年左右的情况。第三部分讲述的是1849年由阿尔弗雷德·本松创立的公司所生产的产品。阿尔弗雷德·尼科莱·本松拥有哥本哈根的天鹅药房。1863年,他创办了一家独立公司,生产品牌药品,从而将药房业务与批发业务结合起来。该家族一直拥有这家公司,直到1952年它转变为一个基金会。经过几轮重组后,药品生产业务以本松制药有限公司的形式持续运营,直到1990年,奈科明制药有限公司收购了所有品牌药品。作为丹麦第一家制药公司,阿尔弗雷德·本松在当时是该国的工业先驱,不仅供应国内市场,还供应国外市场。阿尔弗雷德·本松是丹麦第一家生产用于麻醉乙醚和麦芽提取物(一种营养制剂)的公司。这两种产品的高品质使其成为有价值的出口商品。在19世纪90年代初,阿尔弗雷德·本松成为丹麦第一家开始以研究为基础从屠宰牛中提取甲状腺提取物的公司。这是长期专注于从丹麦畜牧业的动物器官中生产器官治疗物质的开端。1932年,该公司的产品系列中有26种这类制剂,其中许多已在市场上销售多年。这些药物包括铁制剂、泡腾盐,随后是磺胺类药物、合成激素和一种抗晕动病药物。

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