Ogden G R, Cowpe J G, Green M W
Department of Dental Surgery, University of Dundee, Scotland.
J Oral Pathol Med. 1990 Feb;19(2):53-5. doi: 10.1111/j.1600-0714.1990.tb00795.x.
The effect of cigarette smoking on the oral mucosa was assessed through the application of quantitative cytomorphometric analysis to smears obtained from clinically normal buccal mucosa. The nuclear (NA) and cytoplasmic (CA) area of cells within each smear were measured using a Vids V semi-automatic image analysis system. Mean values for NA (smokers--78.74 microns 2, non-smokers--72.28 microns 2 and for CA (smokers--3273.9 microns 2, non-smokers--3098.96 microns 2) were obtained. A two-sample t-test revealed a significant elevation in NA for smokers, but no significant variation in CA between the two groups. These results would suggest that for normal buccal mucosa smoking does appear to influence cytomorphology.
通过对取自临床正常颊黏膜的涂片进行定量细胞形态计量分析，评估吸烟对口腔黏膜的影响。使用Vids V半自动图像分析系统测量每个涂片内细胞的核面积（NA）和细胞质面积（CA）。得出NA的平均值（吸烟者——78.74平方微米，非吸烟者——72.28平方微米）以及CA的平均值（吸烟者——3273.9平方微米，非吸烟者——3098.96平方微米）。双样本t检验显示吸烟者的NA显著升高，但两组之间的CA无显著差异。这些结果表明，对于正常颊黏膜，吸烟似乎确实会影响细胞形态。
