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加拿大首例耐多药白喉棒状杆菌分离自皮肤脓肿。

Canada's first case of a multidrug-resistant Corynebacterium diphtheriae strain, isolated from a skin abscess.

机构信息

University of Alberta, Department of Medical Microbiology, Edmonton, Alberta, Canada.

出版信息

J Clin Microbiol. 2011 Nov;49(11):4003-5. doi: 10.1128/JCM.05296-11. Epub 2011 Aug 31.

DOI:10.1128/JCM.05296-11
PMID:21880960
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3209081/
Abstract

A toxigenic Corynebacterium diphtheriae biovar mitis sequence type 136 (ST136) strain was recovered from a toe infection of an unvaccinated patient recently returned from India. The isolate was resistant to clindamycin, erythromycin (ermX positive), tetracycline, and trimethoprim-sulfamethoxazole, intermediate to ceftriaxone and cefotaxime, and had high MICs for telithromycin and chloramphenicol but was sensitive to other drugs.

摘要

一株产毒白喉棒状杆菌温和生物型 136 型（ST136）菌株从一名最近从印度返回的未接种疫苗患者的脚趾感染中分离得到。该分离株对克林霉素、红霉素（ermX 阳性）、四环素和甲氧苄啶-磺胺甲恶唑耐药，对头孢曲松和头孢噻肟中介，对替考拉宁和氯霉素的 MIC 值较高，但对其他药物敏感。

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本文引用的文献

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Multilocus sequence types of invasive Corynebacterium diphtheriae isolated in the Rio de Janeiro urban area, Brazil.巴西里约热内卢市区分离的侵袭性白喉棒状杆菌的多位点序列型。
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Cutaneous diphtheria in the urban poor population of Vancouver, British Columbia, Canada: a 10-year review.加拿大不列颠哥伦比亚省温哥华市贫困城区人口的皮肤白喉：10 年回顾。
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Multilocus sequence typing identifies evidence for recombination and two distinct lineages of Corynebacterium diphtheriae.多位点序列分型鉴定出白喉棒状杆菌存在重组证据和两个不同的谱系。
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An increase in non-toxigenic Corynebacterium diphtheriae infections in Poland--molecular epidemiology and antimicrobial susceptibility of strains isolated from past outbreaks and those currently circulating in Poland.波兰非产毒株白喉棒状杆菌感染的增加——从过去暴发疫情和目前在波兰流行的菌株中分离出的菌株的分子流行病学和抗菌药物敏感性。
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