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Xpert MTB/RIF 快速诊断细针抽吸活检标本中的结核性淋巴结炎。

Xpert MTB/RIF for rapid diagnosis of tuberculous lymphadenitis from fine-needle-aspiration biopsy specimens.

机构信息

Division of Anatomical Pathology, National Health Laboratory Service, Tygerberg Hospital, Tygerberg, Cape Town, South Africa.

出版信息

J Clin Microbiol. 2011 Nov;49(11):3967-70. doi: 10.1128/JCM.01310-11. Epub 2011 Aug 31.

DOI:10.1128/JCM.01310-11
PMID:21880965
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3209093/
Abstract

This study demonstrates the excellent diagnostic accuracy of the Xpert MTB/RIF test in patients with tuberculous lymphadenitis. The test sensitivity and specificity were 96.7% (95% confidence interval [CI], 86.6 to 100%) and 88.9% (95% CI, 69.6 to 100%), respectively, and it correctly identified 6/6 (100%) of the cytology smear-negative/culture-positive cases and 1 of 2 (50%) rifampin-resistant cases.

摘要

本研究表明 Xpert MTB/RIF 试验在结核性淋巴结炎患者中的诊断准确性极佳。该试验的敏感性和特异性分别为 96.7%（95%置信区间[CI]，86.6 至 100%）和 88.9%（95%CI，69.6 至 100%），它正确识别了 6/6（100%）例细胞学涂片阴性/培养阳性病例和 2 例利福平耐药病例中的 1 例（50%）。

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Diagn Cytopathol. 2010 Jul;38(7):482-8. doi: 10.1002/dc.21223.
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