Biochemistry Department, Military Hospital Instruction Mohamed V, Hay Ryad, Rabat, Morocco.
Rheumatol Int. 2012 Oct;32(10):3303-7. doi: 10.1007/s00296-011-2093-6. Epub 2011 Sep 1.
The aim of this study was to describe biological features and aetiology of monoclonal gammopathy diagnosed during a 10-year period in the biochemistry department of the Moroccan Military Hospital Mohamed V in Rabat. The study was performed from 1 January 2000 to 31 December 2009. The records of 261 patients living in the Rabat area in which either serum protein electrophoresis and serum and/or urine immunofixation were performed at the biochemistry department of Military Instruction Hospital in Rabat were analysed. A cohort of 182 (70%) men and 79 (30%) women, the mean ± SD (range) ages were 60.21 ± 12.56 years. All patients were Caucasian. Electrophoresis found that 211 (80.84%) of the patients had a monoclonal gammopathy. Immunofixation confirmed that 251 (96.17%) patients had a monoclonal band in serum. In our cohort, MM was the most frequent diagnosis, our patients were late diagnosed.
本研究旨在描述在摩洛哥拉巴特的穆罕默德五世军事医院的生化部门在十年间诊断的单克隆丙种球蛋白病的生物学特征和病因。该研究于 2000 年 1 月 1 日至 2009 年 12 月 31 日进行。对在拉巴特地区居住的 261 名患者的记录进行了分析,这些患者在拉巴特的军事教学医院的生化部门进行了血清蛋白电泳和血清和/或尿液免疫固定。该队列包括 182 名(70%)男性和 79 名(30%)女性,平均年龄为 60.21 ± 12.56 岁。所有患者均为高加索人。电泳发现 211 名(80.84%)患者有单克隆丙种球蛋白病。免疫固定证实 251 名(96.17%)患者血清中有单克隆带。在我们的队列中,多发性骨髓瘤是最常见的诊断,我们的患者诊断较晚。