Groenenberg I A, Stijnen T, Wladimiroff J W
Department of Obstetrics and Gynaecology, Erasmus University Rotterdam, The Netherlands.
Pediatr Res. 1990 Apr;27(4 Pt 1):379-82. doi: 10.1203/00006450-199004000-00011.
Maximum flow velocity waveforms were recorded in a longitudinal study from the fetal ascending aorta and fetal pulmonary artery in 46 normal pregnancies and, in addition, from the umbilical artery in 21 cases of intrauterine growth retardation between 19 and 33 wk gestation. In normal pregnancy, the mean peak systolic velocity (PSV) in the ascending aorta increased from 49.4 cm/s at 19 wk of gestation to 79.0 cm/s at 33 wk of gestation. The corresponding increase in PSV in the pulmonary artery was from 39.0 to 63.7 cm/s. The ratio for the PSV between the two arteries remained constant (1.25-1.29). Mean values of PSV in both arteries were linearly related to gestational age. Normal limits according to age were constructed by establishing the 5th and 95th percentiles. In intrauterine growth retardation, the PSV in the pulmonary artery was decreased (less than 5th percentile) in 95% of cases, PSV in the ascending aorta was reduced (less than 5th percentile) in only 57%. No relationship was established between PSV in both arteries and the presence or absence of end-diastolic flow velocities in the umbilical artery. The outcome of fetuses with intrauterine growth retardation, as expressed by Apgar score at 1 min and umbilical cord pH, bears no relationship to the PSV in ascending aorta and pulmonary artery.
在一项纵向研究中，记录了46例正常妊娠胎儿升主动脉和肺动脉的最大流速波形，此外，还记录了21例妊娠19至33周宫内生长受限胎儿的脐动脉最大流速波形。在正常妊娠中，升主动脉的平均收缩期峰值流速（PSV）从妊娠19周时的49.4cm/s增加到妊娠33周时的79.0cm/s。肺动脉PSV的相应增加为从39.0cm/s至63.7cm/s。两条动脉之间的PSV比值保持恒定（1.25 - 1.29）。两条动脉的PSV平均值均与胎龄呈线性相关。通过确定第5和第95百分位数构建了按年龄划分的正常范围。在宫内生长受限中，95%的病例肺动脉PSV降低（低于第5百分位数），升主动脉PSV降低（低于第5百分位数）的仅占57%。两条动脉的PSV与脐动脉舒张末期流速的有无之间未建立关联。宫内生长受限胎儿的结局，以1分钟时的阿氏评分和脐血pH值表示，与升主动脉和肺动脉的PSV无关。
