Department of Radiology, St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Youido-dong, Yongdungpo-gu, Seoul 150-713, Korea.
Jpn J Radiol. 2011 Aug;29(7):475-82. doi: 10.1007/s11604-011-0584-8. Epub 2011 Sep 1.
The aim of this study was to evaluate the imaging findings of invasive lobular carcinoma (ILC) compared to those of invasive ductal carcinoma (IDC).
The study included ILCs (n = 27) and IDCs (n = 85). Imaging findings were retrospectively evaluated, according to the BI-RADS lexicon. We compared the imaging findings, multiplicity, and magnetic resonance imaging (MRI) detection accuracy of ILC with those of IDC.
At mammography, normal findings and mass lesions were more frequent with ILCs (14.8% and 59.2%, respectively) than with IDCs (1.2% and 44.7%, respectively) (P = 0.009). With ultrasonography (US), posterior acoustic shadowing was more frequently seen in ILCs (59.2%) than in IDCs (15.8%) (P < 0.001). With MRI, both ILCs and IDCs most commonly appeared as a heterogeneously enhancing, irregular mass with a spiculated border. Multifocality was more frequently associated with ILCs (40.7%) than with IDCs (14.1% 1% 0.002). However, multicentricity and bilaterality were not different between the two groups. The sensitivity and specificity of MRI for the detection of multiplicity were 91.6% and 73.3%, respectively, for ILCs and 83.3% and 80.3%, respectively, for IDCs.
Normal findings, mass lesions on mammography, and posterior acoustic shadowing on US were more frequently associated with ILCs than with IDCs. Multifocality was more prevalent with ILCs than with IDCs.
本研究旨在评估浸润性小叶癌（ILC）与浸润性导管癌（IDC）的影像学表现。
本研究纳入了 27 例 ILC 和 85 例 IDC。根据 BI-RADS 词汇表，回顾性评估了影像学表现。我们比较了 ILC 和 IDC 的影像学表现、多发性和磁共振成像（MRI）检测准确性。
在乳房 X 线摄影中，正常表现和肿块病变在 ILC 中更为常见（分别为 14.8%和 59.2%），而在 IDC 中则较少见（分别为 1.2%和 44.7%）（P = 0.009）。在超声检查中，ILC 后声影更为常见（59.2%），而 IDC 则较少见（15.8%）（P < 0.001）。在 MRI 上，ILC 和 IDC 最常见的表现为不均匀增强、不规则的毛刺状肿块。多灶性在 ILC 中更为常见（40.7%），而在 IDC 中则较少见（14.1%、1%、0.002）。然而，多中心性和双侧性在两组之间没有差异。MRI 对多发性的敏感性和特异性分别为 91.6%和 73.3%，用于检测 ILC，83.3%和 80.3%，用于检测 IDC。
在 ILC 中，正常表现、乳房 X 线摄影中的肿块病变和超声中的后声影比 IDC 更为常见。多灶性在 ILC 中比 IDC 更为常见。
