Department of Surgery, School of Medicine, Sungkyunkwan University, Kangbuk Samsung Hospital, Seoul, Korea.
Dermatol Surg. 2011 Dec;37(12):1747-53. doi: 10.1111/j.1524-4725.2011.02128.x. Epub 2011 Aug 24.
Prediction of whether postoperative wound healing will result in a hypertrophic scar or keloid is difficult. Diverse treatment options have been developed in an effort to prevent excessive scar formation.
To evaluate the efficacy and safety of a 532-nm potassium titanyl phosphate (KTP) laser in the prevention of scar formation after total thyroidectomy.
Twenty-eight individuals with Fitzpatrick skin types IV and V and linear surgical suture lines after total thyroidectomy by the same surgeon were enrolled. Twenty participants were treated using a 532-nm KTP laser two times at 2-week intervals. Eight participants were assigned to the control group. The Vancouver Scar Scale (VSS), global assessment score (GAS), and participants' subjective satisfaction were used to determine the effect of scar prevention. These results were compared with those of the control group.
The average VSS score was remarkably lower in the KTP laser treatment group. Average GASs indicated better cosmetic outcomes in the treatment group. Participant satisfaction was also higher in the treatment group. No significant side effects were observed during follow-up.
A 532-nm KTP laser can be used safely and efficiently on Asian skin to reduce scar formation after thyroidectomy. The authors have indicated no significant interest with commercial supporters.
预测术后伤口愈合是否会导致增生性瘢痕或瘢痕疙瘩较为困难。为了预防过度瘢痕形成，已经开发出了多种治疗选择。
评估 532nm 掺钛钾酸锂（KTP）激光在预防甲状腺全切除术后瘢痕形成中的疗效和安全性。
28 名皮肤类型为 IV 型和 V 型的个体和同一位外科医生行甲状腺全切除术后线性缝合线的个体纳入研究。20 名参与者使用 532nm KTP 激光治疗两次，间隔 2 周。8 名参与者被分配到对照组。温哥华瘢痕量表（VSS）、总体评估评分（GAS）和参与者的主观满意度用于确定瘢痕预防效果。将这些结果与对照组进行比较。
KTP 激光治疗组的平均 VSS 评分显著降低。平均 GAS 表明治疗组的美容效果更好。治疗组的患者满意度也更高。随访期间未观察到明显的不良反应。
532nm KTP 激光可安全有效地用于亚洲皮肤，减少甲状腺切除术后的瘢痕形成。作者表示与商业支持者没有重大利益关系。
