Artzi Ofir, Friedman Or, Al-Niaimi Firas, Wolf Yoram, Mehrabi Joseph N
Department of Dermatology, Tel Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
The Plastic and Reconstructive Surgery Department, Tel Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Plast Reconstr Surg Glob Open. 2020 Apr 24;8(4):e2746. doi: 10.1097/GOX.0000000000002746. eCollection 2020 Apr.
Most postsurgical scars are considered esthetically and functionally acceptable. Currently, there is no definite consensus treatment for postsurgical scarring. The purpose of this review is to shed some light on the value of scar mitigation and the efficacy of different lasers employed on postsurgical wounds.
A systematic literature review and computational analysis were conducted to identify relevant clinical articles that pertained to the use of lasers for mitigating postsurgical scars. Articles included the National Institutes of Health-National Center for Biotechnology Information-PubMed search and sources cited from relevant studies after 1995. Trials that attributed pre- and posttreatment scores of scar severity based on a verified scar evaluation scale (eg, Patient and Observer Scar Assessment Scale, Vancouver Scar Scale, Global Assessment Scale) were chosen. Clinical assessments varied for each study. To adequately assess the efficacy of the modalities, the final scaled scar appearance scores were realigned and normalized to a standard scale for unbiased comparison.
After filtering through a total of 124 studies, 14 relevant studies were isolated and thus included in the review. Studied lasers were as follows: Pulsed dye laser (PDL), carbon dioxide, diode, potassium titanyl phosphate (KTP), and erbium glass (Er-Glass) lasers.
Treatment with lasers in the postsurgical wound healing phase is safe, effective, and advised in mitigation of pathologic scar formation.
大多数术后瘢痕在美观和功能上被认为是可以接受的。目前，对于术后瘢痕形成尚无明确的共识性治疗方法。本综述的目的是阐明减轻瘢痕的价值以及不同激光用于术后伤口的疗效。
进行了一项系统的文献综述和计算分析，以确定与使用激光减轻术后瘢痕相关的临床文章。文章包括美国国立医学图书馆 - 国家生物技术信息中心 - PubMed搜索以及1995年后相关研究引用的来源。选择了根据经过验证的瘢痕评估量表（例如，患者和观察者瘢痕评估量表、温哥华瘢痕量表、整体评估量表）得出瘢痕严重程度治疗前和治疗后评分的试验。每个研究的临床评估各不相同。为了充分评估这些方法的疗效，将最终的瘢痕外观量表评分重新调整并标准化为一个标准量表，以便进行无偏比较。
在筛选了总共124项研究后，分离出14项相关研究并纳入本综述。所研究的激光如下：脉冲染料激光（PDL）、二氧化碳激光、二极管激光、磷酸钛钾（KTP）激光和铒玻璃（Er-Glass）激光。
在术后伤口愈合阶段使用激光治疗对于减轻病理性瘢痕形成是安全、有效的，并且是建议采用的。
