Department of Ophthalmology, New Zealand National Eye Centre, Faculty of Medical and Health Sciences, University of Auckland, New Zealand.
Clin Exp Ophthalmol. 2012 Mar;40(2):148-54. doi: 10.1111/j.1442-9071.2011.02671.x. Epub 2011 Oct 20.
To evaluate efficacy, safety and predictability of apodized, diffractive multifocal intraocular lenses.
Prospective, observational study. PARTICIPANTS OR SAMPLE: Two hundred three patients (363 eyes) underwent surgery for cataract (54.8%) or clear lens extraction (45.2%).
A study of consecutive patients undergoing lens extraction with insertion of the AcrySof Natural ReSTOR intraocular lens (SN60D3). Assessment included: refraction, corneal topography, biometry, monocular and binocular uncorrected and best spectacle corrected distance and near visual acuity.
Visual acuity, spectacle dependence.
Mean preoperative best corrected visual acuity was 6/12 (cataract) and 6/6 (clear lens extraction). One hundred sixty-one (98.2%) of the clear lens extraction group were hyperopic and presbyopic (mean spherical equivalent +4.25±3.5D). Postoperatively uncorrected visual acuity was ≥6/12 in 96.5% of eyes (51.9% ≥6/6) and ≥ N5 in 95% of eyes. At 6 months, 182 eyes (91.4%) (cataract) and 137 eyes (83.5%) (clear lens extraction) were ≤0.50 D of target spherical equivalent. Spectacle independence was reported in 81.9% (n=168). Minor halos or other visual phenomena were reported in 10.2%. No subjects required intraocular lens exchange. Safety index at 6 months was 2.5 and 1.17 for cataract and clear lens extraction, respectively.
The apodized, diffractive multifocal intraocular lens predictably provided excellent near uncorrected visual acuity and good distance uncorrected visual acuity following cataract and clear lens extraction surgery with a high rate of spectacle independence. A minority of subjects note halos and other visual phenomena that may be related to intraocular lens design.
评估渐变折射多焦点人工晶状体的疗效、安全性和可预测性。
前瞻性、观察性研究。
203 名患者（363 只眼）因白内障（54.8%）或无晶状体眼（45.2%）接受手术。
对连续接受晶状体提取并植入 AcrySof Natural ReSTOR 人工晶状体（SN60D3）的患者进行研究。评估包括：屈光度、角膜地形图、生物测量、单眼和双眼未矫正和最佳矫正远、近视力。
视力、眼镜依赖度。
术前最佳矫正视力平均为 6/12（白内障）和 6/6（无晶状体眼）。无晶状体眼组 161 例（98.2%）为远视和老视（平均等效球镜+4.25±3.5D）。术后未矫正视力≥6/12 的眼占 96.5%（51.9%≥6/6），≥N5 的眼占 95%。术后 6 个月，182 只眼（91.4%）（白内障）和 137 只眼（83.5%）（无晶状体眼）等效球镜误差≤0.50D。81.9%（n=168）报告无需戴眼镜。10.2%报告有轻微的光晕或其他视觉现象。无患者需要更换人工晶状体。术后 6 个月白内障和无晶状体眼的安全指数分别为 2.5 和 1.17。
渐变折射多焦点人工晶状体可预测性地为白内障和无晶状体眼手术后提供卓越的近距未矫正视力和良好的远距未矫正视力，且有较高的不依赖眼镜比例。少数患者注意到光晕和其他可能与人工晶状体设计有关的视觉现象。
