Bass D H, Oliver S, Bornman P C
Department of Surgery, Bacteriology, University of Cape Town.
S Afr Med J. 1990 May 19;77(10):509-11.
Over a 6-month period 5 patients with obstructive jaundice developed Gram-negative septicaemia, all within 48 hours of undergoing endoscopic retrograde cholangiopancreatography. The sepsis proved fatal in 3 patients, despite prompt decompression of the obstructed biliary system. In all cases the organism responsible was Pseudomonas aeruginosa and the source of infection appeared to be a contaminated water-bottle attached to the endoscopic apparatus. This report highlights the importance of disinfection techniques and reviews the present situation in respect of antibiotic prophylaxis.
在6个月的时间里，5例梗阻性黄疸患者发生了革兰氏阴性菌败血症，均在接受内镜逆行胰胆管造影术后48小时内发病。尽管对梗阻性胆道系统进行了及时减压，但仍有3例患者因败血症死亡。所有病例中，致病微生物均为铜绿假单胞菌，感染源似乎是附着在内镜设备上的一个受污染的水瓶。本报告强调了消毒技术的重要性，并对目前抗生素预防的情况进行了综述。
