Department of Urology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
BJU Int. 2012 Mar;109(6):918-24. doi: 10.1111/j.1464-410X.2011.10463.x. Epub 2011 Aug 24.
To systematically review and compare tubeless percutaneous nephrolithotomy (PCNL) with standard PCNL.
We conducted a review of the English language literature on studies involving randomized controlled trials for PCNL. The studies chosen to be included in our review compared tubeless PCNL with standard PCNL and described the advantages of each in the outcomes. Two reviewers independently screened the studies for eligibility, evaluated their quality and extracted the data from the eligible studies, with confirmation by cross-checking. Data were processed using RevMan 5.0.
Seven studies involving 1365 cases met the inclusion criteria, and these were included in the meta-analysis. The patients' baseline characteristics were comparable in all the studies. By comparing the four common characteristics, we found no difference in efficacy between the two surgical approaches in terms of mean operation duration and postoperative haematocrit change (P > 0.05). We found that the mean analgesic requirement and number of days in hospital were lower for tubeless PCNL (P < 0.05).
Our results show that tubeless PCNL is a good option in non-complicated cases, with the advantages of reduced hospital stay and little need for postoperative analgesia. There was no difference between the two approaches in operation duration, or haematocrit change after surgery. As only few studies with small study populations were available, more high quality larger trials with longer follow-up are recommended.
系统地回顾和比较无管经皮肾镜取石术(PCNL)与标准 PCNL。
我们对涉及 PCNL 的随机对照试验的英文文献进行了综述。选择纳入本综述的研究比较了无管 PCNL 与标准 PCNL,并描述了每种方法在结果方面的优势。两名审查员独立筛选研究的合格性,评估其质量并从合格研究中提取数据,并通过交叉核对进行确认。使用 RevMan 5.0 处理数据。
符合纳入标准的 7 项研究共涉及 1365 例患者,纳入荟萃分析。所有研究中患者的基线特征均相似。通过比较四个常见特征,我们发现两种手术方法在手术持续时间和术后血细胞比容变化方面的疗效无差异(P>0.05)。我们发现无管 PCNL 的平均镇痛需求和住院天数较低(P<0.05)。
我们的结果表明,无管 PCNL 是一种非复杂病例的良好选择,具有降低住院时间和术后镇痛需求少的优点。两种方法在手术持续时间或术后血细胞比容变化方面没有差异。由于只有少数研究人群较小的研究可用,建议进行更多高质量、大样本、随访时间更长的试验。