Department of Dermatology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104-6100, USA.
Cell Stem Cell. 2011 Sep 2;9(3):183-4. doi: 10.1016/j.stem.2011.08.009.
Chromatin modifications are important for embryonic stem cell (ESC) pluripotency, but their functions in adult stem cells are less clear. In this issue of Cell Stem Cell, Lien et al. (2011) delineate histone methylation patterns in hair follicle stem cells and show that these marks differ from those of ESCs.
染色质修饰对于胚胎干细胞(ESC)的多能性很重要,但它们在成体干细胞中的功能尚不清楚。在本期《Cell Stem Cell》杂志上,Lien 等人(2011)描绘了毛囊干细胞中的组蛋白甲基化模式,并表明这些标记与 ESC 中的标记不同。