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腹腔镜脾切除术治疗巨脾的可行性和安全性:一项对比研究。

The feasibility and safety of laparoscopic splenectomy for massive splenomegaly: a comparative study.

机构信息

Department of Gastrointestinal Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, China.

出版信息

J Surg Res. 2011 Nov;171(1):e55-60. doi: 10.1016/j.jss.2011.06.040. Epub 2011 Jul 19.

DOI:10.1016/j.jss.2011.06.040
PMID:21885066
Abstract

BACKGROUND

Laparoscopic splenectomy used for massive splenomegaly is still controversial. The purpose of our current study was to identify the feasibility and safety of laparoscopic splenectomy for massive splenomegaly.

METHODS

From January 2006 to January 2010, laparoscopic splenectomy was performed on 33 patients with massive splenomegaly in our hospital, compared with 29 patients who received open splenectomy (group 2) and 48 patients with normal-size spleens who underwent laparoscopic splenectomy (group 3). Perioperative outcomes of these patients were compared.

RESULTS

Compared with patients in group 2, the patients in group 1 required more operative time, less blood transfusion, and a shorter postoperative hospital stay; furthermore, patients in group 1 had less estimated blood loss and fewer complications. No statistically significant difference was found in the patients' spleen volume and spleen weight. Group 1 had statistically significant differences in operative time, estimated blood loss, postoperative hospital stay, spleen volume, and spleen weight compared with patients in group 3. No significant differences were found in the conversion, blood transfusion, or complication rate.

CONCLUSIONS

Laparoscopic splenectomy is a technically feasible and safe procedure for splenomegaly.

摘要

背景

腹腔镜脾切除术用于巨脾仍然存在争议。我们目前的研究目的是确定腹腔镜脾切除术治疗巨脾的可行性和安全性。

方法

从 2006 年 1 月至 2010 年 1 月,我院对 33 例巨脾患者进行了腹腔镜脾切除术,与 29 例行开腹脾切除术的患者(第 2 组)和 48 例行腹腔镜脾切除术的正常大小脾患者(第 3 组)进行了比较。比较这些患者的围手术期结果。

结果

与第 2 组患者相比,第 1 组患者的手术时间更长,输血更少,术后住院时间更短;此外,第 1 组患者的估计出血量更少,并发症更少。三组患者的脾脏体积和脾脏重量无统计学差异。第 1 组在手术时间、估计出血量、术后住院时间、脾脏体积和脾脏重量方面与第 3 组患者有显著差异。转换率、输血率或并发症发生率无显著差异。

结论

腹腔镜脾切除术治疗脾肿大是一种技术上可行且安全的方法。

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