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2
t(1:14) and trisomy 4 in a patient with concomitant leukaemias.一名合并白血病患者出现1号与14号染色体易位及4号染色体三体异常。
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Clinical characteristics of patients with de novo acute myeloid leukaemia and isolated trisomy 11: a Cancer and Leukemia Group B study.初发急性髓系白血病合并单纯11号染色体三体患者的临床特征:一项癌症与白血病B组研究
Br J Haematol. 1998 Jun;101(3):513-20. doi: 10.1046/j.1365-2141.1998.00714.x.
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Trisomy 11 in myelodysplastic syndrome-derived acute myeloblastic leukaemias.骨髓增生异常综合征衍生的急性髓系白血病中的11号染色体三体
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Complex translocation (6;21;8), a variant of t(8;21), with trisomy 4 in a patient with acute myelogenous leukemia (M2).复杂易位(6;21;8),t(8;21)的一种变异型,急性髓性白血病(M2)患者伴有4号染色体三体。
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Eosinophilia and granulocytic dysplasia terminating in acute myeloid leukaemia after 24 years.嗜酸性粒细胞增多和粒细胞发育异常24年后发展为急性髓系白血病。
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Trisomy 14: a recurring cytogenetic abnormality associated with myeloid disorders.14号染色体三体:一种与髓系疾病相关的复发性细胞遗传学异常。
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Sea-blue histiocytosis in a patient with acute myeloid leukemia with myelodysplasia-related changes harboring isolated trisomy 9: pathognomonic or a coincidence?一名患有急性髓系白血病伴骨髓发育异常相关改变且孤立性9号染色体三体的患者出现海蓝色组织细胞增多症:是具有诊断意义还是巧合?
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Pathological findings in the complete trisomy 9 syndrome: three case reports and review of the literature.9号染色体完全三体综合征的病理发现:三例病例报告及文献复习
Pediatr Dev Pathol. 2008 Jan-Feb;11(1):23-9. doi: 10.2350/06-08-0143.1.
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Positive biochemical screening for trisomy 18: on the path of trisomy 9.18三体综合征的阳性生化筛查:在9三体的道路上。
Prenat Diagn. 2008 Feb;28(2):162-4. doi: 10.1002/pd.1927.
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Prenatal diagnosis of complete trisomy 9: a case report and review of the literature.9号染色体完全三体的产前诊断:一例病例报告及文献复习
Am J Perinatol. 2006 Feb;23(2):131-5. doi: 10.1055/s-2006-931804.
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Identification of novel cytogenetic markers with prognostic significance in a series of 968 patients with primary myelodysplastic syndromes.在968例原发性骨髓增生异常综合征患者中鉴定具有预后意义的新型细胞遗传学标志物。
Haematologica. 2005 Sep;90(9):1168-78.
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Nonrandom aneuploidy of chromosomes 1, 5, 6, 7, 8, 9, 11, 12, and 21 induced by the benzene metabolites hydroquinone and benzenetriol.苯代谢产物对苯二酚和苯三酚诱导的1、5、6、7、8、9、11、12和21号染色体的非随机非整倍性。
Environ Mol Mutagen. 2005 May;45(4):388-96. doi: 10.1002/em.20103.
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Molecular genetics and cytogenetics of myeloproliferative disorders.骨髓增殖性疾病的分子遗传学和细胞遗传学
Baillieres Clin Haematol. 1998 Dec;11(4):819-48. doi: 10.1016/s0950-3536(98)80041-3.
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Trisomy 9 in a patient with secondary acute myelogenous leukemia detected by fluorescent in situ hybridization.荧光原位杂交检测继发性急性髓系白血病患者的9号染色体三体。
Pathobiology. 1999 Mar-Apr;67(2):111-4. doi: 10.1159/000028059.
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The importance of diagnostic cytogenetics on outcome in AML: analysis of 1,612 patients entered into the MRC AML 10 trial. The Medical Research Council Adult and Children's Leukaemia Working Parties.诊断细胞遗传学对急性髓系白血病预后的重要性:对参加医学研究委员会AML 10试验的1612例患者的分析。医学研究委员会成人及儿童白血病工作组。
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Prenatal diagnosis of nonmosaic trisomy 9 and related ultrasound findings at 11.7 weeks.孕11.7周时非嵌合型9三体综合征的产前诊断及相关超声表现
J Matern Fetal Med. 1998 Jan-Feb;7(1):48-50. doi: 10.1002/(SICI)1520-6661(199801/02)7:1<48::AID-MFM11>3.0.CO;2-H.
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Primary, single, autosomal trisomies associated with haematological disorders. United Kingdom Cancer Cytogenetics Group (UKCCG).与血液系统疾病相关的原发性、单一常染色体三体。英国癌症细胞遗传学小组(UKCCG)。
Leuk Res. 1992 Sep;16(9):841-51. doi: 10.1016/0145-2126(92)90030-b.

急性髓系白血病FAB M2型患者出现9号染色体三体:一种罕见情况。

Trisomy 9 in a Patient with Acute Myelogenous Leukaemia FAB Type M2: A Rare Occurrence.

作者信息

Chaubey R, Sazawal S, Dada R, Sharma P, Pathak D, Saxena R

出版信息

Indian J Hematol Blood Transfus. 2010 Sep;26(3):103-5. doi: 10.1007/s12288-010-0035-1. Epub 2010 Oct 22.

DOI:10.1007/s12288-010-0035-1
PMID:21886394
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3002086/
Abstract

Complete trisomy 9 is a rare cytogenetic abnormality in haematological malignancies. Here we present the case history of a patient with clinical diagnosis of acute myeloblastic leukaemia (FAB type M2) and having trisomy 9 with adverse outcome.

摘要

9号染色体完全三体是血液系统恶性肿瘤中一种罕见的细胞遗传学异常。在此,我们报告一例临床诊断为急性髓细胞白血病(FAB分型M2型)且伴有9号染色体三体并预后不良的患者的病例史。