Poirel H, Jonveaux P, Daniel M T, Berger R
Unité INSERM U301, Institut de Génétique Moléculaire, Paris, France.
Leuk Lymphoma. 1995 May;17(5-6):455-7. doi: 10.3109/10428199509056857.
Trisomy 14 as single karyotype aberration was detected in three patients, two with acute myeloblastic leukemia, AML-M2 type, and one with aplastic anemia. These new observations and the 28 previously reported cases confirm that trisomy 14 is a primary non random change, mostly confined to myeloid disorders.
在三名患者中检测到14号染色体三体作为单一核型异常，其中两名患有急性髓细胞白血病，AML-M2型，一名患有再生障碍性贫血。这些新的观察结果以及之前报道的28例病例证实，14号染色体三体是一种主要的非随机变化，主要局限于髓系疾病。
