HSS J. 2010 Sep;6(2):155-9. doi: 10.1007/s11420-010-9155-2. Epub 2010 Feb 25.
Total knee arthroplasty (TKA) is a commonly performed procedure for the treatment of end-stage arthritis of the knee. Pain control following TKA is difficult to manage in some patients. We examined the use of a postoperative intraarticular injection of 100 mL of 0.2% (200 mg) ropivacaine in a double-blind, prospective, placebo-controlled pilot study to evaluate its use as a pain control modality. All patients received general anesthesia. Postoperatively, patients were placed on intravenous patient-controlled analgesia with morphine. The ropivacaine group showed an early trend in lower visual analog scale (VAS) scores when compared with the placebo group. Patients receiving ropivacaine used a similar amount of narcotics compared with the placebo group. Intraarticular ropivacaine used for pain control after TKA demonstrated no statistically significant difference in lowering VAS scores or narcotic usage; therefore, intraarticular ropivacaine as a single modality is not recommended for effective pain management.
全膝关节置换术（TKA）是治疗膝关节晚期关节炎的常用方法。有些患者在 TKA 后难以控制疼痛。我们研究了在一项双盲、前瞻性、安慰剂对照的初步研究中，使用 100 毫升 0.2%（200 毫克）罗哌卡因关节内注射作为疼痛控制方式的效果。所有患者均接受全身麻醉。术后，患者接受静脉自控镇痛（吗啡）。与安慰剂组相比，罗哌卡因组的视觉模拟评分（VAS）早期呈现出较低的趋势。与安慰剂组相比，接受罗哌卡因的患者使用了类似数量的麻醉药物。用于 TKA 后疼痛控制的关节内罗哌卡因在降低 VAS 评分或麻醉药物使用方面没有统计学意义上的显著差异；因此，不建议将关节内罗哌卡因作为单一方法用于有效的疼痛管理。
