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本文引用的文献

1
3D ingrowth of bovine articular chondrocytes in biodegradable cryogel scaffolds for cartilage tissue engineering.牛关节软骨细胞在可生物降解的冷冻凝胶支架中的 3D 内生长用于软骨组织工程。
J Tissue Eng Regen Med. 2011 Nov;5(10):770-9. doi: 10.1002/term.375. Epub 2010 Dec 29.
2
Tissue ingrowth after implantation of a novel, biodegradable polyurethane scaffold for treatment of partial meniscal lesions.新型可生物降解聚氨酯支架植入治疗半月板部分损伤后的组织内生长。
Am J Sports Med. 2011 Apr;39(4):774-82. doi: 10.1177/0363546511398040. Epub 2011 Mar 7.
3
Improving bone formation in a rat femur segmental defect by controlling bone morphogenetic protein-2 release.通过控制骨形态发生蛋白-2 的释放来改善大鼠股骨节段性缺损中的骨形成。
Tissue Eng Part A. 2011 Jul;17(13-14):1735-46. doi: 10.1089/ten.TEA.2010.0446. Epub 2011 Apr 3.
4
Nanogel-based scaffold delivery of prostaglandin E(2) receptor-specific agonist in combination with a low dose of growth factor heals critical-size bone defects in mice.基于纳米凝胶的支架递送前列腺素E(2)受体特异性激动剂并联合低剂量生长因子可治愈小鼠的临界尺寸骨缺损。
Arthritis Rheum. 2011 Apr;63(4):1021-33. doi: 10.1002/art.30151.
5
Evaluation of a hydrogel-fiber composite for ACL tissue engineering.水凝胶纤维复合材料在 ACL 组织工程中的评价。
J Biomech. 2011 Feb 24;44(4):694-9. doi: 10.1016/j.jbiomech.2010.10.043. Epub 2010 Dec 15.
6
Effect of a scaffold fabricated thermally from acetylated PLGA on the formation of engineered cartilage.热致乙酰化 PLGA 支架对工程化软骨形成的影响。
Macromol Biosci. 2011 Feb 11;11(2):267-74. doi: 10.1002/mabi.201000315. Epub 2010 Nov 15.
7
Biocompatibility and osteogenesis of biomimetic Bioglass-Collagen-Phosphatidylserine composite scaffolds for bone tissue engineering.用于骨组织工程的仿生 Bioglass-胶原蛋白-磷脂酰丝氨酸复合支架的生物相容性和成骨作用。
Biomaterials. 2011 Feb;32(4):1051-8. doi: 10.1016/j.biomaterials.2010.09.068. Epub 2010 Oct 25.
8
Microscale versus nanoscale scaffold architecture for mesenchymal stem cell chondrogenesis.微尺度与纳米尺度支架结构对间充质干细胞软骨分化的影响。
Tissue Eng Part A. 2011 Mar;17(5-6):831-40. doi: 10.1089/ten.TEA.2010.0409. Epub 2010 Dec 14.
9
Effects of bioactive glass nanoparticles on the mechanical and biological behavior of composite coated scaffolds.生物活性玻璃纳米粒子对复合涂层支架的力学和生物学行为的影响。
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10
Toward modeling the bone marrow niche using scaffold-based 3D culture systems.使用基于支架的 3D 培养系统来模拟骨髓龛。
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支架在肌肉骨骼组织工程中的应用。

The use of scaffolds in musculoskeletal tissue engineering.

作者信息

Henson Frances, Getgood Alan

机构信息

Department of Veterinary Medicine, University of Cambridge, Cambridge, CB3 0ES, UK.

出版信息

Open Orthop J. 2011;5 Suppl 2:261-6. doi: 10.2174/1874325001105010261. Epub 2011 Jul 28.

DOI:10.2174/1874325001105010261
PMID:21886690
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3149868/
Abstract

The use of bioengineering scaffolds remains an integral part of the tissue engineering concept. A significant amount of basic science and clinical research has been focused on the regeneration of musculoskeletal tissues including bone, articular cartilage, meniscus, ligament and tendon. This review aims to provide the reader with a summary of the principals of using material scaffolds in musculoskeletal tissue engineering applications and how these materials may eventually come to be incorporated in clinical practice.

摘要

生物工程支架的应用仍然是组织工程概念的一个重要组成部分。大量的基础科学和临床研究都集中在肌肉骨骼组织的再生上,包括骨骼、关节软骨、半月板、韧带和肌腱。这篇综述旨在向读者总结在肌肉骨骼组织工程应用中使用材料支架的原理,以及这些材料最终如何应用于临床实践。