手部孤立性丛状神经鞘瘤
Isolated plexiform schwannoma of the hand.
作者信息
Wollina Uwe, Langner Dana, Gruner Monika, Schönlebe Jaqueline, Haroske Gunter
机构信息
Department of Dermatology and Allergology and.
出版信息
J Dermatol Case Rep. 2008 Jul 7;2(2):28-30. doi: 10.3315/jdcr.2008.1011.
BACKGROUND
The plexiform schwannoma, a peripheral nerve sheath tumor, is a very rare entity. But dermatologists should be familiar with since they may be the first who make diagnosis possible by taking a deep biopsy.
MAIN OBSERVATION
A 24-year-old male presented with multiple asymptomatic subcutaneous nodules of the palmar side of his right hand. Histologic investigations revealed a plexiform schwannoma with numerous Antoni-A areas. There was no evidence of neurofibromatosis type 1 or 2.
CONCLUSIONS
Plexiform schwannoma of the hand is a rare nerve sheath tumor. In individual (symptomatic) cases hand surgery is an option that needs a critical indication. In every case histologic investigations are mandatory to confirm the diagnosis and not to overlook the malignant variant of this disease.
背景
丛状神经鞘瘤是一种周围神经鞘瘤，是一种非常罕见的疾病。但皮肤科医生应该熟悉它，因为他们可能是通过进行深部活检而使诊断成为可能的首批医生。
主要观察结果
一名24岁男性，右手掌侧出现多个无症状的皮下结节。组织学检查显示为具有大量Antoni-A区的丛状神经鞘瘤。没有1型或2型神经纤维瘤病的证据。
结论
手部丛状神经鞘瘤是一种罕见的神经鞘瘤。在个别（有症状的）病例中，手部手术是一种需要严格适应症的选择。在每种情况下，组织学检查都是确认诊断并避免忽视该疾病恶性变体的必要手段。
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