Martinez Roxana, Oladimeji Akinola Emmanuel, Wilson Robert H
Department of Orthopaedic Surgery, Howard University Hospital, Washington, DC.
J Hand Surg Glob Online. 2023 Apr 3;5(3):371-374. doi: 10.1016/j.jhsg.2023.01.005. eCollection 2023 May.
Plexiform schwannomas are rare, benign, neural crest-derived tumors that commonly occur in the hand and upper extremities. They may be sporadic or associated with neurofibromatosis type 2. Although previous literature has described plexiform schwannomas occurring in fingers, nerve and tendon sheaths, and intraosseous lesions, this is the first known case of a plexiform schwannoma of the thumb. This is a case of a growing, painless, subungual mass of the thumb in a 54-year-old patient. After surgical excision and subsequent immunohistochemical examination, the patient was diagnosed with a plexiform schwannoma. This highlights the importance of maintenance a broad differential before surgery and obtaining a proper diagnosis using histopathology.
丛状神经鞘瘤是一种罕见的良性神经嵴源性肿瘤，常见于手部和上肢。它们可能是散发性的，也可能与2型神经纤维瘤病相关。尽管先前的文献描述过丛状神经鞘瘤发生于手指、神经和腱鞘以及骨内病变，但这是已知的首例拇指丛状神经鞘瘤病例。这是一名54岁患者拇指上一个逐渐增大、无痛的甲下肿物的病例。经过手术切除及后续免疫组化检查，该患者被诊断为丛状神经鞘瘤。这凸显了术前保持广泛鉴别诊断以及利用组织病理学进行准确诊断的重要性。
