2nd Propedeutical Department of Surgery, Medical School, Hippokratio General Hospital, Aristotle University of Thessaloniki, 49 Konstantinoupoleos str, PC, 54642 Thessaloniki, Greece.
Tech Coloproctol. 2011 Oct;15 Suppl 1:S5-8. doi: 10.1007/s10151-011-0738-9.
Colonic diverticular disease is extremely common in developed countries. Although the majority of patients with diverticulosis remain asymptomatic, about one-third of the patients manifest the disease with either hemorrhage or inflammation. Diverticulitis may be uncomplicated or complicated by abscess formation, perforation with peritonitis, fistula, intestinal obstruction, or stricture. Controversy exists regarding the aggressiveness of diverticulitis during recurrent attacks of the disease as well as in special groups of patients including immunocompromised patients, young patients, and patients with right-sided disease. Clinical characteristics of symptomatic uncomplicated disease can be similar to irritable bowel syndrome, while acute diverticulitis is sometimes difficult to distinguish from segmental colitis associated with diverticulosis. The considerable clinical overlap between those entities with diverticular disease demonstrates that there are still areas of uncertainty in their physiopathology.
结肠憩室病在发达国家极为常见。尽管大多数憩室病患者无症状，但约有三分之一的患者出现出血或炎症。憩室炎可无并发症，也可并发脓肿形成、穿孔合并腹膜炎、瘘管、肠梗阻或狭窄。在疾病反复发作期间以及在免疫功能低下患者、年轻患者和右侧疾病患者等特殊人群中，憩室炎的侵袭性存在争议。有症状的单纯性疾病的临床特征可能与肠易激综合征相似，而急性憩室炎有时难以与与憩室病相关的节段性结肠炎区分。憩室病这些实体之间存在相当大的临床重叠，这表明它们的病理生理学仍存在不确定领域。
