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制定急性右半结肠憩室炎患者的治疗指南。

Toward therapeutic guidelines for patients with acute right colonic diverticulitis.

作者信息

Komuta Ko, Yamanaka Shizuo, Okada Kazuya, Kamohara Yukio, Ueda Takeshi, Makimoto Noriaki, Shiogama Toshiaki, Furui Junichiro, Kanematsu Takashi

机构信息

Division of Colon and Rectal Surgery, Department of Surgery, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1, Sakamoto, Ngasaki 852-8102, Japan.

出版信息

Am J Surg. 2004 Feb;187(2):233-7. doi: 10.1016/j.amjsurg.2003.11.009.

Abstract

BACKGROUND

At present, little information is available on the outcome of medical therapy for patients with acute right colonic diverticulitis, and this has meant a gap in constructing guidelines for its treatment.

METHODS

The records of patients with acute right colonic diverticulitis at Nagasaki University Graduate School and affiliated hospitals were reviewed and analyzed with the goal of establishing therapeutic guidelines. The time frame of the data analyzed was from 1984 to 2002.

RESULTS

Of the 81 patients included in the data, 80 patients who were suffering a first attack were successfully treated with bowel rest and antibiotics. Two of these 80 patients underwent an elective operation at the surgeon's discretion during the original hospitalization and 1 (1.2%) needed an urgent operation. Of the 78 patients who responded to medical therapy, 16 (20.5%) developed recurrent right colonic diverticulitis. All 16 patients who had a second attack were successfully treated with medical therapy. Three of the 16 patients underwent an elective operation during this rehospitalization period. Of the 13 patients who had had a second attack and had responded to medical therapy, there was a third attack in 2 patients (15.4%). Both of these patients were again successfully treated with medical therapy. There has been no morbidity and no mortality related to recurrence to date. The average time from the first attack to us contacting the patient was 35.2 months.

CONCLUSIONS

Unlike acute uncomplicated left colonic diverticulitis, our findings indicate that after two documented episodes, medical treatment alone rather than elective surgery may be considered as an effective guideline for the treatment of acute uncomplicated right colonic diverticulitis.

摘要

背景

目前,关于急性右半结肠憩室炎患者药物治疗的结果,可获取的信息较少,这意味着在制定其治疗指南方面存在空白。

方法

回顾并分析了长崎大学研究生院及其附属医院中急性右半结肠憩室炎患者的病历记录,目的是制定治疗指南。所分析数据的时间范围是1984年至2002年。

结果

在纳入数据的81例患者中,80例首次发作的患者通过肠道休息和使用抗生素成功治愈。这80例患者中有2例在初次住院期间由外科医生酌情进行了择期手术,1例(1.2%)需要急诊手术。在对药物治疗有反应的78例患者中,16例(20.5%)发生了复发性右半结肠憩室炎。所有16例第二次发作的患者均通过药物治疗成功治愈。这16例患者中有3例在此次再次住院期间接受了择期手术。在13例第二次发作且对药物治疗有反应的患者中,有2例(15.4%)发生了第三次发作。这2例患者再次通过药物治疗成功治愈。迄今为止,尚未出现与复发相关的发病和死亡情况。从首次发作到我们联系患者的平均时间为35.2个月。

结论

与急性非复杂性左半结肠憩室炎不同,我们的研究结果表明,在有两次记录发作后,对于急性非复杂性右半结肠憩室炎的治疗,单独药物治疗而非择期手术可被视为一种有效的治疗指南。

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