Reactions under the click chemistry philosophy employed in supramolecular and mechanostereochemical systems.

Supramolecular chemistry and mechanostereochemistry have been major beneficiaries of the concepts and reactions pioneered under the "click chemistry" philosophy. The success of the copper(I) 1,3-dipolar cycloaddition between azides and alkynes, resulting in the triazole ring has inspired the application of other emerging click reactions, for example, Diels-Alder cycloadditions, thiol-ene/yne chemistry, and nitrile N-oxide cycloadditions, towards the creation of advanced functional supramolecular and mechanostereochemical systems. In this Focus Review, recent advances in the use of click chemistry in these fields are highlighted.