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基于解剖学、文化和分子生物学线索的朝鲜人骨骼性别鉴定。

Sex determination of Joseon people skeletons based on anatomical, cultural and molecular biological clues.

机构信息

Department of Anatomy, Ewha Womans University School of Medicine, Yangcheon-gu, Seoul, Republic of Korea.

出版信息

Ann Anat. 2011 Dec 20;193(6):539-43. doi: 10.1016/j.aanat.2011.07.002. Epub 2011 Jul 30.

DOI:10.1016/j.aanat.2011.07.002
PMID:21889322
Abstract

Sex determination is very integral to examinations conducted by anatomists on human skeletons discovered in the archaeological field. In Korea, as in other countries, cultural or anatomical information has been the tool of first resort in making such determinations. In cases in which anatomical examination has revealed only borderline characteristics, PCR-based analysis of X/Y-chromosome genes has been employed. Even so, there are as yet very few reports on how accurately the respective results correspond with each other. In this study on 34 examined medieval Korean skeletons, 11 (32.3%) showed perfectly matching results for the three methods of sex determination. In the cases in which the cultural and anatomical findings were discordant, the amelogenin assay corroborated either the former or the latter. Although we must admit the relatively limited role of aDNA analysis, when only very small amounts of amplifiable DNA remain, we believe that the amelogenin assay can be very meaningful to Korean anatomists when employed in adjunct to conventional anatomically or culturally based sex determination.

摘要

性别鉴定对于考古领域发现的人类骨骼进行解剖学家检查非常重要。在韩国,和其他国家一样,文化或解剖学信息一直是进行这种鉴定的首选工具。在解剖检查只显示出边缘特征的情况下,则采用基于聚合酶链反应(PCR)的 X/Y 染色体基因分析。即便如此,关于各自结果的准确性如何相互对应,仍然很少有报道。在这项对 34 具中世纪韩国骨骼的研究中,11 具(32.3%)骨骼的三种性别鉴定方法结果完全一致。在文化和解剖学发现不一致的情况下,牙釉蛋白检测结果与前者或后者相符。虽然我们必须承认 aDNA 分析的作用相对有限,但当只有非常少量可扩增的 DNA 时,我们认为牙釉蛋白检测在与传统的基于解剖学或文化的性别鉴定结合使用时,对韩国解剖学家非常有意义。

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