Department of Integrative Physiology, National Institute for Physiological Sciences, Okazaki, Japan.
Neuroimage. 2012 Jan 16;59(2):1501-7. doi: 10.1016/j.neuroimage.2011.08.024. Epub 2011 Aug 26.
The role of sensory information in motor control has been studied, but the cortical processing underlying cross-modal relationship between visual and somatosensory information for movement execution remains a matter of debate. Visual estimates of limb positions are congruent with proprioceptive estimates under normal visual conditions, but a mismatch between the watched and felt movement of the hand disrupts motor execution. We investigated whether activation in somatosensory areas was affected by the discordance between the intended and an executed action. Subjects performed self-paced thumb movement of the left hand under normal visual and mirror conditions. The Mirror condition provided a non-veridical and unexpected visual feedback. The results showed activity in the primary somatosensory area to be inhibited and activity in the secondary somatosensory area (SII) to be enhanced with voluntary movement, and neural responses in the SII and parietal cortex were strongly affected by the unexpected visual feedback. These results provide evidence that the visual information plays a crucial role in activation in somatosensory areas during motor execution. A mechanism that monitors sensory inputs and motor outputs congruent with current intension is necessary to control voluntary movement.
感觉信息在运动控制中的作用已经得到了研究，但是对于视觉和体感信息在运动执行中的跨模态关系的皮层处理仍然存在争议。在正常视觉条件下，肢体位置的视觉估计与本体感觉估计是一致的，但是手的观察到的和感觉到的运动之间的不匹配会破坏运动执行。我们研究了感觉区域的激活是否受到意图和执行动作之间的不匹配的影响。受试者在正常视觉和镜像条件下进行左手自主拇指运动。镜像条件提供了非真实和意外的视觉反馈。结果表明，初级体感区的活动被抑制，次级体感区（SII）的活动增强，并且 SII 和顶叶皮层中的神经反应强烈受到意外视觉反馈的影响。这些结果提供了证据，表明在运动执行过程中，视觉信息在体感区域的激活中起着至关重要的作用。需要有一种机制来监测与当前意图一致的感觉输入和运动输出，以控制自愿运动。
