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院外心脏骤停后结局的年龄特异性差异。

Age-specific differences in outcomes after out-of-hospital cardiac arrests.

机构信息

Department of Emergency Medicine, Osaka Medical College, Takatsuki City, Osaka 569-8686, Japan.

出版信息

Pediatrics. 2011 Oct;128(4):e812-20. doi: 10.1542/peds.2010-3886. Epub 2011 Sep 2.

DOI:10.1542/peds.2010-3886
PMID:21890823
Abstract

OBJECTIVE

We assessed out-of-hospital cardiac arrests (OHCAs) for various pediatric age groups.

METHODS

This prospective, population-based, observational study included all emergency medical service-treated OHCAs in Osaka, Japan, between 1999 and 2006 (excluding 2004). Patients were grouped as adults (>17 years), infants (<1 year), younger children (1-4 years), older children (5-12 years), and adolescents (13-17 years). The primary outcome measure was 1-month survival with favorable neurologic outcome.

RESULTS

Of 950 pediatric OHCAs, resuscitations were attempted for 875 patients (92%; 347 infants, 203 younger children, 135 older children, and 190 adolescents). The overall incidence of nontraumatic pediatric OHCAs was 7.3 cases per 100 000 person-years, compared with 64.7 cases per 100 000 person-years for adults and 65.5 cases per 100 000 person-years for infants. Most infant OHCAs occurred in homes (93%) and were not witnessed (90%). Adolescent OHCAs often occurred outside the home (45%), were witnessed by bystanders (37%), and had shockable rhythms (18%). One-month survival was more common after nontraumatic pediatric OHCAs than adult OHCAs (8% [56 of 740 patients] vs 5% [1677 of 33 091 patients]; adjusted odds ratio: 2.26 [95% confidence interval: 1.63-3.13]). One-month survival with favorable neurologic outcome was more common among children than adults (3% [21 of 740 patients] vs 2% [648 of 33 091 patients]; adjusted odds ratio: 2.46 [95% confidence interval: 1.45-4.18]). Rates of 1-month survival with favorable neurologic outcome were 1% for infants, 2% for younger children, 2% for older children, and 11% for adolescents.

CONCLUSION

Survival and favorable neurologic outcome at 1 month were more common after pediatric OHCAs than adult OHCAs.

摘要

目的

我们评估了不同儿科年龄组的院外心脏骤停(OHCA)。

方法

本前瞻性、基于人群的观察性研究纳入了 1999 年至 2006 年期间日本大阪所有接受急救医疗服务的 OHCA(不包括 2004 年)。患者分为成人(>17 岁)、婴儿(<1 岁)、幼儿(1-4 岁)、大龄儿童(5-12 岁)和青少年(13-17 岁)。主要结局指标为 1 个月时具有良好神经功能结局的生存率。

结果

在 950 例儿科 OHCA 中,对 875 例患者进行了复苏尝试(92%;347 例婴儿,203 例幼儿,135 例大龄儿童,190 例青少年)。非创伤性儿科 OHCA 的总发生率为每 100000 人年 7.3 例,而成人和婴儿的发生率分别为每 100000 人年 64.7 例和 65.5 例。大多数婴儿 OHCA 发生在家庭中(93%)且未被目击(90%)。青少年 OHCA 常发生在家庭外(45%),由旁观者目击(37%),且具有可除颤节律(18%)。非创伤性儿科 OHCA 后 1 个月生存率高于成人 OHCA(8%[740 例患者中的 56 例]与 5%[33091 例患者中的 1677 例];调整后的优势比:2.26[95%置信区间:1.63-3.13])。儿童 1 个月生存率优于成人(3%[740 例患者中的 21 例]与 2%[33091 例患者中的 648 例];调整后的优势比:2.46[95%置信区间:1.45-4.18])。1 个月时具有良好神经功能结局的生存率分别为婴儿 1%、幼儿 2%、大龄儿童 2%和青少年 11%。

结论

儿科 OHCA 后生存率和 1 个月时的良好神经功能结局更为常见。

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