Vollertsen R S
Mayo Medical School, Mayo Clinic, Rochester, Minnesota.
Rheum Dis Clin North Am. 1990 May;16(2):433-9.
Cogan's syndrome is a rare syndrome manifested by nonsyphilitic interstitial keratitis and audiovestibular symptoms including hearing loss, tinnitus, and vertigo. Systemic manifestations may occur. Systemic vasculitis and aortic insufficiency secondary to aortitis and valvulitis are two of the most serious manifestations.
科根综合征是一种罕见的综合征,表现为非梅毒性间质性角膜炎以及听觉前庭症状,包括听力丧失、耳鸣和眩晕。也可能出现全身表现。系统性血管炎以及由主动脉炎和瓣膜炎继发的主动脉瓣关闭不全是最严重的两种表现。