Lubenow T R, Ivankovich A D
Department of Anesthesiology, Rush-Presbyterian-St. Luke's Medical Center, Chicago, Illinois 60612.
Semin Surg Oncol. 1990;6(3):173-6. doi: 10.1002/ssu.2980060308.
Inadequate pain relief remains a problem for many patients with cancer. Narcotic administration by the epidural or subarachnoid route is a relatively recent innovation and is indicated when pain is poorly controlled with high doses of systemic narcotics, or when patients experience limiting narcotic side effects. When given by the epidural or intrathecal route, narcotics have a longer duration of action and a lower dose is effective. These techniques involve personnel trained in catheter insertion and maintenance. Epidural and intrathecal administration of narcotics is an alternative when oral narcotics are ineffective. In this report the term "intraspinal" refers to epidural and/or subarachnoid placement of catheters and drugs.
对许多癌症患者来说,疼痛控制不足仍是一个问题。通过硬膜外或蛛网膜下途径给予麻醉剂是一项相对较新的创新方法,当大剂量全身性麻醉剂无法有效控制疼痛,或患者出现麻醉剂副作用限制时使用。通过硬膜外或鞘内途径给药时,麻醉剂作用时间更长,较低剂量即可起效。这些技术需要经过导管插入和维护培训的人员操作。当口服麻醉剂无效时,硬膜外和鞘内给予麻醉剂是一种替代方法。在本报告中,“脊髓内”一词指导管和药物的硬膜外和/或蛛网膜下放置。