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减重手术后的医学随访:营养和药物问题。预防和治疗营养缺乏的一般建议。

Medical follow up after bariatric surgery: nutritional and drug issues. General recommendations for the prevention and treatment of nutritional deficiencies.

机构信息

Unité Multidisciplinaire de Chirurgie de l'Obésité, CHU de Nancy.

出版信息

Diabetes Metab. 2009 Dec;35(6 Pt 2):544-57. doi: 10.1016/S1262-3636(09)73464-0.


DOI:10.1016/S1262-3636(09)73464-0
PMID:20152742
Abstract

This review is an update of the long-term follow-up of nutritional and metabolic issues following bariatric surgery, and also discusses the most recent guidelines for the three most common procedures: adjustable gastric bands (AGB); sleeve gastrectomy (SG); and roux-en-Y gastric bypass (GBP). The risk of nutritional deficiencies depends on the percentage of weight loss and the type of surgical procedure performed. Purely restrictive procedures (AGB, SG), for example, can induce digestive symptoms, food intolerance or maladaptative eating behaviours due to pre- or postsurgical eating disorders. GBP also has a minor malabsorptive component. Iron deficiency is common with the three types of bariatric surgery, especially in menstruating women, and GBP is also associated with an increased risk of calcium, vitamin D and vitamin B12 deficiencies. Rare deficiencies can lead to serious complications such as encephalopathy or protein-energy malnutrition. Long-term problems such as changes in bone metabolism or neurological complications need to be carefully monitored. In addition, routine nutritional screening, recommendations for appropriate supplements and monitoring compliance are imperative, whatever the bariatric procedure. Key points are: (1) virtually routine mineral and multivitamin supplementation; (2) prevention of gallstone formation with the use of ursodeoxycholic acid during the first 6 months; and (3) regular, life-long, follow-up of all patients. Pre- and postoperative therapeutic patient education (TPE) programmes, involving a new multidisciplinary approach based on patient-centred education, may be useful for increasing patients'long-term compliance, which is often poor. The role of the general practitioner has also to be emphasized: clinical visits and follow-ups should be monitored and coordinated with the bariatric team, including the surgeon, the obesity specialist, the dietitian and mental health professionals.

摘要

这篇综述更新了减重手术后营养和代谢问题的长期随访结果,并讨论了三种最常见手术的最新指南:可调胃束带术(AGB);胃袖状切除术(SG);胃旁路术(GBP)。营养缺乏的风险取决于减重百分比和手术类型。例如,纯粹的限制性手术(AGB、SG)由于术前或术后的饮食障碍,可能会引起消化症状、食物不耐受或适应性进食行为。GBP 也有轻微的吸收不良成分。三种类型的减重手术都会导致缺铁,尤其是在月经期间,而且 GBP 还会增加钙、维生素 D 和维生素 B12 缺乏的风险。罕见的缺乏会导致严重的并发症,如脑病或蛋白质-能量营养不良。需要仔细监测长期问题,如骨代谢变化或神经并发症。此外,无论采用哪种减重手术,常规的营养筛查、适当补充剂的建议和监测依从性都是至关重要的。关键点如下:(1)几乎常规的矿物质和多种维生素补充;(2)在最初的 6 个月内使用熊去氧胆酸预防胆结石形成;(3)所有患者都要定期、终身、随访。术前和术后治疗性患者教育(TPE)计划,涉及基于以患者为中心的教育的新的多学科方法,可能有助于提高患者的长期依从性,而患者的依从性往往很差。全科医生的作用也需要强调:临床访视和随访应与减重团队(包括外科医生、肥胖专家、营养师和心理健康专业人员)进行监测和协调。

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