Queensland Centre for Gynaecologic Cancer, Royal Brisbane and Women's Hospital, Queensland, Australia.
Int J Gynecol Cancer. 2011 Dec;21(9):1579-84. doi: 10.1097/IGC.0b013e318227c9ac.
Current international guidelines recommend routine hysterectomy in the initial surgical management of epithelial ovarian cancer. However, there seems to be limited evidence to support these recommendations. We examined the data for a series of women undergoing hysterectomy as part of surgical management of ovarian cancer. Most of the women who underwent hysterectomy had no macroscopic uterine involvement in the ovarian cancer. However, almost half of them had macroscopic residual disease at completion of cytoreductive surgery. The incidence of synchronous primary endometrial cancers was 5%, and preoperative ultrasound had a sensitivity of 82% for predicting endometrial pathology. We also surveyed the members of the Australian Society of Gynaecological Oncologists (ASGO) regarding the role of hysterectomy in the management of ovarian cancer. Most of the respondents indicated that they believe hysterectomy should be routinely performed in the management of ovarian cancer but acknowledge that there is a lack of evidence to support the practice.
目前的国际指南建议在卵巢上皮癌的初始手术治疗中常规行子宫切除术。然而，似乎没有足够的证据支持这些建议。我们对一系列因卵巢癌而接受子宫切除术的女性患者的数据进行了检查。大多数接受子宫切除术的女性患者的卵巢癌并无肉眼可见的子宫受累。然而，几乎一半的患者在完成肿瘤细胞减灭术时仍有肉眼可见的残留病灶。同步原发性子宫内膜癌的发病率为 5%，术前超声检查预测子宫内膜病变的敏感性为 82%。我们还对澳大利亚妇科肿瘤学家协会（ASGO）的成员就子宫切除术在卵巢癌治疗中的作用进行了调查。大多数受访者表示，他们认为在卵巢癌的治疗中应常规行子宫切除术，但也承认目前缺乏支持这一做法的证据。
