Nat Rev Neurol. 2011 Sep 5;7(9):479-80. doi: 10.1038/nrneurol.2011.118.
The diagnosis of rapidly progressive dementias (RPDs), particularly sporadic Creutzfeldt–Jakob disease (sCJD), can prove challenging. Treatable RPDs might mimic sCJD, which is currently untreatable. A recent review of a large cohort of patients with suspected CJD highlights the extent of misdiagnosis and possible sources of error.
快速进展性痴呆(RPD)的诊断,特别是散发性克雅氏病(sCJD),可能具有挑战性。可治疗的 RPD 可能类似于目前无法治疗的 sCJD。最近对一组疑似克雅氏病患者的大型队列研究强调了误诊的程度和可能的错误来源。