Lee Kyung-Kyu, Kang Dong-Hun, Kim Yong-Sun, Park Jaechan
Department of Neurosurgery, Daegu-Gyeongbuk Cardiocerebrovascular Center, Kyungpook National University, Daegu, Korea.
J Korean Neurosurg Soc. 2011 Jul;50(1):45-7. doi: 10.3340/jkns.2011.50.1.45. Epub 2011 Jul 31.
Abnormal contrast enhancement on brain computed tomography (CT) scan after diagnostic or interventional angiography is not rare, and has known to be induced by temporary blood-brain barrier (BBB) disruption from contrast media. Furthermore, it has been regarded as clinically subtle, but reported to have no symptom or mild transient symptoms. However, we recently experienced two cases of serious BBB disruption during the acute period after coiling of an unruptured intracranial aneurysm. One patient presented with an unruptured paraclinoid internal carotid artery (ICA) aneurysm on the right and the other with an unruptured right supraclinoid ICA aneurysm. Both patients showed similar findings on immediate postembolization CT scan and clinical courses after coiling. Typical radiological, clinical characteristics of BBB disruption were described. In addition, the role of immediate postembolization CT scan are also discussed.
在诊断性或介入性血管造影术后，脑部计算机断层扫描（CT）出现异常对比增强并不罕见，已知这是由造影剂导致的血脑屏障（BBB）暂时破坏引起的。此外，它在临床上被认为较为隐匿，但据报道没有症状或仅有轻微的短暂症状。然而，我们最近遇到了两例在未破裂颅内动脉瘤栓塞术后急性期发生严重血脑屏障破坏的病例。一名患者右侧存在未破裂的床突旁颈内动脉（ICA）动脉瘤，另一名患者右侧存在未破裂的床突上ICA动脉瘤。两名患者在栓塞术后即刻CT扫描及栓塞后的临床过程中均表现出相似的结果。描述了血脑屏障破坏典型的影像学和临床特征。此外，还讨论了栓塞术后即刻CT扫描的作用。
