Department of Chemistry, Kansas State University, Manhattan, Kansas 66506, USA.
Chem Commun (Camb). 2011 Nov 7;47(41):11411-3. doi: 10.1039/c1cc14124d. Epub 2011 Sep 5.
Resorcinarene-based cavitands functionalized with acetamido groups capable of self-complementary hydrogen-bond interactions, were synthesized in order to construct supramolecular capsules. The 1,3-bifunctionalized cavitand produced a polymeric assembly, whereas the tetra-functionalized analogue yielded a discrete capsule held together via N-H···O hydrogen bonds. The ethynyl species attached to the rim of these host molecules deepen each cavitand and expands the volume of the resulting capsule.
为了构建超分子胶囊，合成了带有乙酰氨基基团的能够进行自互补氢键相互作用的间苯二酚衍生的空腔化合物。1,3-双功能化的空腔化合物产生了聚合组装，而四功能化的类似物则产生了离散的胶囊，通过 N-H···O 氢键结合在一起。连接在这些主体分子边缘的乙炔基加深了每个空腔化合物的深度，并扩展了所得胶囊的体积。
