Kishimoto Nozomu, Takao Tetsuya, Yamamoto Keisuke, Tsujihata Masao, Nonomura Norio, Yamamoto Masaki, Mizuki Misao, Hara Tsuneo
The Department of Urology, Osaka University Graduate School of Medicine.
Hinyokika Kiyo. 2011 Aug;57(8):445-9.
A 79-year-old man presented with a chief complaint of difficulty in urination. Digital rectal examination and transrectal ultrasonography showed an enlarged prostate. Holmium laser enucleation of the prostate (HoLEP) was performed. Histological findings revealed diffuse large B-cell lymphoma by immunohistochemical studies. Pelvic Lymph nodes were swollen on fluoro deoxygiucose-positron emission tomography examination. Therefore, the disease was classified into clinical stage II according to Ann Arbor's criteria. The patient achieved complete response after 6 cycles of combination chemotherapy with rituximab, pirarubicin, cyclophosphamide, vincristine, and prednisolone (R-THP-COP). Now, 1 year 8 months after the chemotherapy, he remains free of the disease.
一名79岁男性因排尿困难为主诉前来就诊。直肠指检和经直肠超声检查显示前列腺增大。遂行钬激光前列腺剜除术（HoLEP）。免疫组织化学研究的组织学结果显示为弥漫性大B细胞淋巴瘤。氟脱氧葡萄糖正电子发射断层扫描检查发现盆腔淋巴结肿大。因此，根据安阿伯标准，该疾病被分类为临床II期。患者在接受6个周期的利妥昔单抗、吡柔比星、环磷酰胺、长春新碱和泼尼松龙联合化疗（R-THP-COP）后达到完全缓解。现在，化疗后1年8个月，他仍无疾病复发。
