Henneberg S, Nilsson A, Hök B, Persson M P
Department of Anaesthesiology and Electronics, Uppsala University, Lund, Sweden.
J Clin Anesth. 1990 Mar-Apr;2(2):76-80. doi: 10.1016/0952-8180(90)90057-a.
During whole body radiation therapy of children, treatment may be done in places not equipped with acceptable scavenging systems for anesthetic gases and where clinical observation of the patient may be impossible. In order to solve this problem, the authors have used a total intravenous (IV) anesthetic technique using midazolam, pancuronium, and fentanyl. With midazolam as the only hypnotic agent, the problem with scavenging is solved, and a computer simulation of the plasma concentration of midazolam is presented. A modified stethoscope for monitoring during radiation also has been developed. This anesthetic technique and the stethoscope have been used in seven children. The total IV anesthesia proved to be a useful method for children during whole body radiation. The modified stethoscope functioned very well and was a useful complement to the monitoring equipment.
在儿童全身放射治疗期间，治疗可能在未配备可接受的麻醉气体清除系统的场所进行，且在此处可能无法对患者进行临床观察。为了解决这个问题，作者采用了一种使用咪达唑仑、泮库溴铵和芬太尼的全静脉麻醉技术。以咪达唑仑作为唯一的催眠剂，解决了清除问题，并给出了咪达唑仑血浆浓度的计算机模拟结果。还开发了一种用于放疗期间监测的改良听诊器。这种麻醉技术和听诊器已应用于7名儿童。全静脉麻醉被证明是儿童全身放疗期间的一种有用方法。改良听诊器运行良好，是监测设备的有益补充。
