Department of Materials Engineering, Isfahan University of Technology, 8415683111 Isfahan, Iran.
J Mater Sci Mater Med. 2011 Nov;22(11):2449-55. doi: 10.1007/s10856-011-4433-1. Epub 2011 Sep 6.
The biphasic calcium phosphate (BCP) yields higher bioactivity and efficiency than the Hydroxyapatite (HA) alone. The HA/β-TCP ratio significantly affects BCP bioactivity as well as the extent of BCP resorption. In this study, the BCP coating on ASTM F-75 cobalt base alloy during the investment casting process was investigated. For this purpose, molten metal was poured at 1,470°C into previously coated investment molds preheated to 750, 850, 950, 1,050°C in order to investigate the effect of mold preheating temperatures on coating phase transformations. For in vitro evaluation, samples were immersed in the simulated body fluid (SBF) at 37°C for 4 weeks and characterized by XRD, SEM, EDS, and optical microscopy. The weight percentages of HA and β-TCP of the specimens were calculated to find that the HA/β-TCP ratio significantly depended on the mold preheating temperature as it caused changes in the dissolution behavior of BCP coating and the bone-like apatite precipitation on coating during in vitro evaluation.
双相磷酸钙（BCP）比单独的羟磷灰石（HA）具有更高的生物活性和效率。HA/β-TCP 比例显著影响 BCP 的生物活性以及 BCP 的吸收程度。在这项研究中，研究了在熔模铸造过程中在 ASTM F-75 钴基合金上涂覆 BCP。为此，将 1470°C 的熔融金属浇入先前预热至 750、850、950、1050°C 的涂覆投资模具中，以研究模具预热温度对涂层相变的影响。为了进行体外评估，将样品在 37°C 的模拟体液（SBF）中浸泡 4 周，并通过 XRD、SEM、EDS 和光学显微镜进行表征。计算了样品中 HA 和β-TCP 的重量百分比，发现 HA/β-TCP 比例显著取决于模具预热温度，因为它导致了 BCP 涂层在体外评估期间的溶解行为和类似骨的磷灰石在涂层上的沉淀发生变化。
