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[呼吸机相关性肺炎的预防:循证治疗是什么?]

[Prevention of ventilator-associated pneumonia: what's evidence-based treatment?].

作者信息

Deja Maria, Trefzer Tanja, Geffers Christine

出版信息

Anasthesiol Intensivmed Notfallmed Schmerzther. 2011 Sep;46(9):560-7. doi: 10.1055/s-0031-1286606. Epub 2011 Sep 5.

Abstract

Patients who suffer from a ventilator-associated pneumonia (VAP) are ventilated longer, stay longer in the ICU and in hospital and therefore lead to higher costs. Despite the therapeutic potential of the VAP nowadays there is about 10% additional mortality observed. Although the clinical VAP diagnosis is limited (sensitivity/specificity) rapid diagnosis promotes treatment (calculated antibiotic therapy) and improves the survival rate. And in the course the review of the VAP diagnosis of unnecessary antibiotics reduces the resistance development in that area and also the selection pressure.

摘要

患有呼吸机相关性肺炎(VAP)的患者机械通气时间更长,在重症监护病房(ICU)和医院的停留时间更长,因此导致更高的费用。尽管如今VAP具有治疗潜力,但仍观察到约10%的额外死亡率。虽然临床VAP诊断存在局限性(敏感性/特异性),但快速诊断可促进治疗(计算性抗生素治疗)并提高生存率。而且在此过程中,对VAP诊断中不必要使用抗生素的审查可降低该领域的耐药性发展以及选择压力。

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