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法国道路交通事故致脊髓损伤未见减少:基于流行趋势的研究。

Spinal cord injuries sustained in road crashes are not on the decrease in france: a study based on epidemiological trends.

机构信息

Translational and Integrative Group in Epilepsy Research, Centre de Recherche en Neurosciences de Lyon, Lyon Neuroscience Center, Université Claude Bernard Lyon, Cedex, France.

出版信息

J Neurotrauma. 2012 Feb 10;29(3):479-87. doi: 10.1089/neu.2011.1880.

Abstract

Traumatic spinal cord injuries (SCI) are rare but extremely costly. In order to improve the modelling of inclusion criteria for studies of SCI it is necessary to determine what epidemiological trends affect SCI. Using the Rhone Registry, which contains all the casualties resulting from road crashes in the Rhône département of France and codes their injuries using the Abbreviated Injury Scale (AIS), we describe the epidemiological trends that affect spinal cord injury (SCI), major spinal trauma (MST) and severe injuries (AIS4+) to other body regions between two periods 1996-2001 and 2003-2008. Although there has been a marked decrease (35%) in the incidence of casualties after a road traffic crash, and reductions of 22% in the incidence of MST and 33% in that of severe injuries (AIS4+) (p<0.001), for SCI the incidence rate and number of casualties have remained surprisingly stable. In the second period, there was no change in the incidence of SCI resulting from road traffic crashes, nor in the associated fatality, mortality and survival rates. The incidence for car users was significantly lower in the second period. This contrasts with the incidences for motorcyclists and for the group including pedestrians and cyclists which were respectively 47% and 77% higher in the second period. The median age of the casualties, the age-adjusted incidence of SCI and the number of associated injuries were also higher in the second period. We have observed a marked reduction in the incidence of road trauma including the most severe injuries, but not SCI. The higher proportion of motorcyclists, the increase in the age of casualties and the greater presence of multiple injuries are new factors in the epidemiology of SCI after a road crash.

摘要

创伤性脊髓损伤(SCI)较为罕见,但治疗费用极高。为了改进 SCI 研究纳入标准的建模,有必要确定哪些流行病学趋势会影响 SCI。利用包含法国罗讷省所有道路事故伤亡人员并使用损伤严重度评分(AIS)对其损伤进行编码的 Rhone 登记处,我们描述了在两个时期(1996-2001 年和 2003-2008 年)影响脊髓损伤(SCI)、主要脊柱创伤(MST)和其他身体部位严重损伤(AIS4+)的流行病学趋势。尽管道路交通事故伤亡人员的发病率显著下降(35%),MST 和严重损伤(AIS4+)的发病率分别下降了 22%和 33%(p<0.001),但 SCI 的发病率和伤亡人数却出人意料地保持稳定。在第二时期,道路交通事故导致的 SCI 发病率以及相关的死亡率、病死率和生存率均无变化。汽车使用者的发病率在第二时期显著降低。这与摩托车手以及包括行人和骑自行车者在内的群体形成鲜明对比,摩托车手和行人和骑自行车者的发病率分别在第二时期增加了 47%和 77%。伤亡人员的中位年龄、年龄调整后的 SCI 发病率和相关损伤数量在第二时期也更高。我们观察到道路创伤的发病率显著下降,包括最严重的损伤,但 SCI 除外。摩托车手的比例较高、伤亡人员年龄增加以及多发性损伤的存在增多是道路事故后 SCI 流行病学的新因素。

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