Johns Hopkins Medical Institutions, Baltimore, Maryland 21205, USA.
Transfusion. 2012 Mar;52(3):560-6. doi: 10.1111/j.1537-2995.2011.03328.x. Epub 2011 Sep 2.
Blood component donations by apheresis has become more common in modern blood transfusion practices. However, apheresis donation still remains less common in China. This study describes the demographic profile and transfusion-transmissible infection (TTI) prevalence among donors making apheresis platelet (AP) donations compared to those making whole blood (WB) donations and the differences among five geographically diverse blood centers in China.
This is a descriptive study using data from all successful donations at the five blood centers in 2008 and 2009. Donor demographic and TTI screening reactive rates were collected for WB and AP donations and blood centers. Logistic regression was used to identify independent factors associated with AP donations.
From January 1, 2008, to December 31, 2009, there were 512,594 WB and 26,199 AP donations at five blood centers. AP donations accounted for 4.9% of all donations. AP donations have lower reactive rate than WB donations for hepatitis B virus surface antigen, hepatitis C virus antibodies, human immunodeficiency virus antibodies, and syphilis screening testing. Males, donors older than 25 years old, non-Han donors, and donors with below high school educational level were more likely to make AP donations. The characteristics of AP donations differed among the five Chinese blood centers.
Our analysis suggests that the characteristics of AP donations in China are different from WB donations and differ among the five Chinese blood centers. Some of the differences are likely due to different recruitment policies. Further studies should be conducted to understand what motivates Chinese blood donors to participate as AP donors.
在现代输血实践中，通过单采术捐献血液成分变得更为常见。然而，在中国，单采术捐献仍然较为少见。本研究描述了与全血捐献者相比，进行单采血小板（AP）捐献者的人口统计学特征和输血传播感染（TTI）流行率，以及中国五个地理位置不同的血站之间的差异。
这是一项描述性研究，使用了 2008 年和 2009 年五个血站所有成功捐献者的数据。收集了全血和 AP 捐献者及血站的人口统计学和 TTI 筛查反应率。使用逻辑回归确定与 AP 捐献相关的独立因素。
从 2008 年 1 月 1 日至 2009 年 12 月 31 日，五个血站共进行了 512594 次全血和 26199 次 AP 捐献。AP 捐献占所有捐献的 4.9%。AP 捐献的乙型肝炎病毒表面抗原、丙型肝炎病毒抗体、人类免疫缺陷病毒抗体和梅毒筛查检测的反应率低于全血捐献。男性、年龄大于 25 岁、非汉族和受教育程度低于高中的捐献者更有可能进行 AP 捐献。五个中国血站的 AP 捐献特征不同。
我们的分析表明，中国的 AP 捐献特征与全血捐献不同，并且在五个中国血站之间存在差异。其中一些差异可能是由于不同的招募政策所致。应进一步开展研究，以了解是什么促使中国献血者作为 AP 献血者参与。
