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Rocuronium and sugammadex: An alternative to succinylcholine for electro convulsive therapy in patients with suspected neuroleptic malignant syndrome.罗库溴铵与舒更葡糖钠：疑似神经阻滞剂恶性综合征患者电休克治疗中琥珀酰胆碱的替代药物
J Anaesthesiol Clin Pharmacol. 2011 Jul;27(3):380-2. doi: 10.4103/0970-9185.83687.
2
Comparison of recovery times from rocuronium-induced muscle relaxation after reversal with three different doses of sugammadex and succinylcholine during electroconvulsive therapy.比较三种不同剂量琥珀酸舒更葡糖钠和琥珀酰胆碱用于电抽搐治疗时罗库溴铵诱导的肌肉松弛逆转后恢复时间。
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Health Technol Assess. 2010 Jul;14(39):1-211. doi: 10.3310/hta14390.
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Use of rocuronium-sugammadex, an alternative to succinylcholine, as a muscle relaxant during electroconvulsive therapy.在电抽搐治疗中使用罗库溴铵-琥珀胆碱作为肌肉松弛剂的替代药物。
J Anesth. 2011 Apr;25(2):286-90. doi: 10.1007/s00540-011-1095-6. Epub 2011 Feb 4.
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Safety and Efficacy of Rocuronium With Sugammadex Reversal Versus Succinylcholine in Outpatient Surgery-A Multicenter, Randomized, Safety Assessor-Blinded Trial.罗库溴铵与舒更葡糖钠逆转剂对比琥珀胆碱用于门诊手术的安全性和有效性——一项多中心、随机、安全性评估者盲法试验
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Rocuronium-sugammadex use for electroconvulsive therapy in a hemodialysis patient: a case report.罗库溴铵-舒更葡糖在一名血液透析患者电休克治疗中的应用：病例报告
JA Clin Rep. 2016;2(1):28. doi: 10.1186/s40981-016-0055-4. Epub 2016 Oct 10.
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The increases in potassium concentrations are greater with succinylcholine than with rocuronium-sugammadex in outpatient surgery: a randomized, multicentre trial.门诊手术中，琥珀酰胆碱引起的钾离子浓度升高幅度大于罗库溴铵-舒更葡糖：一项随机多中心试验。
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Comparison of emergence agitation between succinylcholine and rocuronium-sugammadex in adults following closed reduction of a nasal bone fracture: a prospective randomized controlled trial.比较琥珀酰胆碱和罗库溴铵-舒更葡糖钠在成人鼻骨骨折闭合复位后苏醒期躁动的前瞻性随机对照试验。
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Study of Rocuronium-Sugammadex as an Alternative to Succinylcholine-Cisatracurium in Microlaryngeal Surgery.罗库溴铵-舒更葡糖钠作为杓状软骨切除术中小剂量琥珀胆碱-顺式阿曲库铵的替代药物的研究。
Laryngoscope. 2021 Jan;131(1):E212-E218. doi: 10.1002/lary.28649. Epub 2020 Apr 23.

引用本文的文献

1
Current evidence on the use of sugammadex for neuromuscular blockade antagonism during electroconvulsive therapy: a narrative review.关于舒更葡糖钠在电休克治疗期间用于拮抗神经肌肉阻滞的当前证据：一项叙述性综述。
Korean J Anesthesiol. 2025 Feb;78(1):3-15. doi: 10.4097/kja.24234. Epub 2024 Oct 7.

本文引用的文献

1
Modified ECT Using Succinylcholine After Remission of Neuroleptic Malignant Syndrome.在抗精神病药恶性综合征缓解后使用琥珀酰胆碱的改良电休克治疗
Convuls Ther. 1987;3(4):284-290.
2
Rapacuronium: why did it fail as a replacement for succinylcholine?
Br J Anaesth. 2002 Feb;88(2):163-5. doi: 10.1093/bja/88.2.163.
3
Rapacuronium: an alternative to succinylcholine for electroconvulsive therapy.罗库溴铵：用于电休克治疗时替代琥珀酰胆碱的药物。
Anesth Analg. 2001 May;92(5):1171-2. doi: 10.1097/00000539-200105000-00018.
4
An unexpected hyperkalemic response to succinylcholine during electroconvulsive therapy for catatonic schizophrenia.
Anesthesiology. 1999 Aug;91(2):574-5. doi: 10.1097/00000542-199908000-00038.
5
A fractured hip during electro-convulsive therapy.
Eur J Anaesthesiol. 1999 Apr;16(4):265-7. doi: 10.1046/j.1365-2346.1999.00463.x.
6
Low dose mivacurium is less effective than succinylcholine in electroconvulsive therapy.在电休克治疗中，低剂量米库氯铵不如琥珀酰胆碱有效。
Can J Anaesth. 1999 Jan;46(1):49-51. doi: 10.1007/BF03012514.
7
Modification of tonic-clonic convulsions by atracurium in multiple-monitored electroconvulsive therapy.
J Clin Anesth. 1993 Jan-Feb;5(1):16-21. doi: 10.1016/0952-8180(93)90082-p.
8
Electroconvulsive therapy.电休克疗法
Psychiatr Clin North Am. 1993 Sep;16(3):497-513.
9
Is mivacurium chloride effective in electroconvulsive therapy? A report of four cases, including a patient with myasthenia gravis.氯化米库氯铵在电休克治疗中是否有效？四例报告，包括一名重症肌无力患者。
Anesth Analg. 1993 Aug;77(2):392-4. doi: 10.1213/00000539-199308000-00030.
10
Use of muscle relaxants for electroconvulsive therapy: how much is enough?用于电休克治疗的肌肉松弛剂：多少剂量才足够？
Anesth Analg. 1994 Jan;78(1):195-6. doi: 10.1213/00000539-199401000-00046.

罗库溴铵与舒更葡糖钠：疑似神经阻滞剂恶性综合征患者电休克治疗中琥珀酰胆碱的替代药物

Rocuronium and sugammadex: An alternative to succinylcholine for electro convulsive therapy in patients with suspected neuroleptic malignant syndrome.

作者信息

Ramamoorthy Karthik G, Downey H, Hawthorne P

机构信息

Department of Anaesthesia, Consultant, Letterkenny General Hospital, Letterkenny, Ireland.

出版信息

J Anaesthesiol Clin Pharmacol. 2011 Jul;27(3):380-2. doi: 10.4103/0970-9185.83687.

DOI:10.4103/0970-9185.83687
PMID:21897513
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3161467/
Abstract

We report a case of presumptive neuroleptic malignant syndrome requiring muscle relaxation for electro-convulsive therapy. short acting muscle relaxation without the use of succinylcholine was achieved using rocvronivm reversed with the novel reversal agent sugammadex. We suggest that this combination is a safe and effective alternative to succinylcholine in such cases.

摘要

我们报告了一例疑似抗精神病药恶性综合征患者，在进行电惊厥治疗时需要使用肌肉松弛剂。使用罗库溴铵并联合新型逆转剂舒更葡糖实现了短效肌肉松弛，且未使用琥珀酰胆碱。我们认为，在这类病例中，这种联合用药是琥珀酰胆碱的一种安全有效的替代方案。