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口腔颌面部病变的细针穿刺细胞学检查:诊断陷阱

Fine needle aspiration cytology in lesions of oral and maxillofacial region: Diagnostic pitfalls.

作者信息

Singh Sunita, Garg Natasha, Gupta Sumiti, Marwah Nisha, Kalra Rajneesh, Singh Virender, Sen Rajeev

机构信息

Departments of Pathology, Pt. B. D. Sharma PGIMS, Rohtak, India.

出版信息

J Cytol. 2011 Jul;28(3):93-7. doi: 10.4103/0970-9371.83461.

Abstract

BACKGROUND

Fine needle aspiration cytology (FNAC) of oral and maxillofacial region has not been widely utilized for diagnosis due to diversity of lesion types, heterogeneity of cell populations and difficulties in reaching and aspirating these lesions.

AIM

Our aim was to demonstrate the effectiveness of this cheap and simple procedure for the diagnosis of tumor and tumor like lesions of oral and maxillofacial region. In addition, we sought to highlight probable causes of errors in the cases showing lack of correlation between cytological and histological diagnoses.

MATERIALS AND METHODS

The study was conducted on 50 patients of all age groups with various palpable lesions in the oromaxillofacial region. A comparison between cytological and histological diagnosis was done wherever biopsy material was available.

RESULTS

The rate of unsatisfactory FNA was 4%. There were six false negative cases but no false positive case. The sensitivity of our study ranged from 77.7 to 75% including and excluding the suspicious cases, respectively. Specificity and positive predictive value was 100%.

CONCLUSION

FNAC is a minimally invasive, highly accurate and cost-effective procedure for the assessment of patients with oromaxillofacial lesions. When applied in a proper manner, FNAC can help avoid a surgical biopsy in many cases.

摘要

背景

由于口腔颌面部病变类型多样、细胞群体异质性以及难以触及和抽吸这些病变,口腔颌面部细针穿刺细胞学检查(FNAC)尚未广泛用于诊断。

目的

我们的目的是证明这种廉价且简单的程序对诊断口腔颌面部肿瘤及肿瘤样病变的有效性。此外,我们试图强调在细胞学和组织学诊断缺乏相关性的病例中可能的错误原因。

材料与方法

对50例口腔颌面部有各种可触及病变的各年龄组患者进行了研究。只要有活检材料,就对细胞学诊断和组织学诊断进行比较。

结果

不满意的FNA率为4%。有6例假阴性病例,但无假阳性病例。我们研究的敏感性分别包括和排除可疑病例,范围为77.7%至75%。特异性和阳性预测值为100%。

结论

FNAC是一种用于评估口腔颌面部病变患者的微创、高度准确且具有成本效益的程序。以适当方式应用时,FNAC在许多情况下可帮助避免手术活检。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6eb8/3159298/fbb21c64c8f4/JCytol-28-93-g005.jpg

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